Exercise Intervention - and Impact on Hospitalization

Status:	Recruiting
Conditions:	Orthopedic
Therapuetic Areas:	Orthopedics / Podiatry
Healthy:	No
Age Range:	18 - Any
Updated:	2/23/2019
Start Date:	March 1, 2017
End Date:	January 2020

Exercise Intervention and Its Impact on Hospitalization - a Mulitcentered Study

Skeletal muscle abnormalities (sarcopenia) and frailty are common complications seen in
patients with end-stage liver disease. The presence of these complications portends poor
prognosis. The purpose of this study is to assess the impact of a formal home based video
strengthening program (REST) on sarcopenia and frailty. We also want to assess the impact of
this exercise program on complication rates, hospitalization, on quality of life (QOL) and on
survival.

inclusion= waitlisted for liver transplant with poor 6MWT

Exclusion criteria include: age < 18 years, recent hospitalization (within 14 days) due to
decompensation, variceal bleeding in the previous 1 month, large esophageal varices without
primary prophylaxis, active excessive alcohol intake (in the previous 3 months), current
overt uncontrolled hepatic encephalopathy, hepatopulmonary syndrome with uncontrolled
hypoxia, portopulmonary hypertension, inability to perform exercise, or marked symptomatic
comorbidities (cardiac, pulmonary, renal). multiorgan transplant

We found this trial at

sites

Mayo Clinic Arizona

13400 E. Shea Blvd.
Scottsdale, Arizona 85259

480-301-8000