Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections

Inclusion Criteria:

- Male or female ≥18 years of age

- Diagnosis of acute bacterial skin and skin structure infection (ABSSSI), with a
regional or systemic sign of infection

- Requirement for intravenous bacterial treatment

Exclusion Criteria:

- Use of any systemic antibacterial treatment within 14 days

- Contraindication to the administration of the study treatments, including known
clinically-relevant hypersensitivity

- Uncomplicated skin and skin structure infection

- Primary ABSSSI due to or associated with any of the following: diabetic foot
infection, gangrene, or perianal abscess; concomitant infection at another site;
infected burns; decubitus, chronic, or ischemic ulcer; evolving necrotizing process;
infections at vascular catheter sites or involving thrombophlebitis

- Requirement for more than two surgical interventions in the operating room

- Severe sepsis or septic shock