Brain Enhancement Training Towards Elders Resilience to Aging

Inclusion Criteria:

- Participant must be a fluent English speaker

- Participant must have adequate sensorimotor capacity to perform the program, including
visual capacity adequate to read from a computer screen at a normal viewing distance,
auditory capacity adequate to understand normal speech, and motor capacity adequate to
control a computer mouse

- Participant must not have evidence of dementia as indicated by the Montreal Cognitive
Assessment (MoCA)

Exclusion Criteria:

- Participant with any medical illnesses, injuries or conditions predisposing to
imminent functional and/or cognitive decline

- Participant requiring caregiver assistance in dressing/personal hygiene

- Participant with severe visual deficits (including visual neglect, partial field cuts,
anopias) and/or severe hearing deficit that would prevent use of the computerized
treatment program

- Participant with recent participation of computer-delivered cognitive training within
2 years of consent

- Participant with claustrophobia or any other contraindication to MRI scanning

- Participant with inability to complete a 1-hour MRI

- Pregnant women

- Participant with any implanted devices above the waist (e.g., cardiac pacemaker or
auto-defibrillators, neural pacemaker, aneurysm clips, cochlear implant, metallic
bodies in the eye or central nervous system, any form of wires or metal devices that
may concentrate radio frequency fields)

- Participants with active suicidal ideations as measured by the Columbia-Suicide
Severity Rating Scale (C-SSRS)