The Effects of Dietary Salt on Post-exercise Hypotension
| Status: | Recruiting |
|---|---|
| Conditions: | High Blood Pressure (Hypertension), Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 40 |
| Updated: | 6/27/2018 |
| Start Date: | May 1, 2018 |
| End Date: | May 1, 2019 |
| Contact: | William B Farquhar, PhD |
| Email: | wbf@udel.edu |
| Phone: | 302-831-6178 |
The new American Heart Association (AHA) blood pressure guidelines are expected to raise the
prevalence of high blood pressure to ~46% in the United States. One recommendation for
lowering blood pressure is aerobic exercise, which produces a period of lowered blood
pressure (post-exercise hypotension; PEH) that lasts up to 24 hours. It is believed that PEH
may be responsible for the observations of lowered blood pressure following initiation of
exercise. However, most Americans eat too much salt, which expands plasma volume and may
prevent PEH, rending aerobic exercise ineffective in improving blood pressure status.
prevalence of high blood pressure to ~46% in the United States. One recommendation for
lowering blood pressure is aerobic exercise, which produces a period of lowered blood
pressure (post-exercise hypotension; PEH) that lasts up to 24 hours. It is believed that PEH
may be responsible for the observations of lowered blood pressure following initiation of
exercise. However, most Americans eat too much salt, which expands plasma volume and may
prevent PEH, rending aerobic exercise ineffective in improving blood pressure status.
Recently released blood pressure guidelines from the American Heart Association and American
College of Cardiology are expected to raise the prevalence of hypertension in America from
~33% to ~46%. A single bout of aerobic exercise produces a prolonged period (up to 24 hours)
of lowered blood pressure (post-exercise hypotension; PEH). Repeated bouts of aerobic
exercise results in maintenance of lowered blood pressure, leading to recommendations of
aerobic exercise for improvement of blood pressure status. However, more than 90% of
Americans consume more sodium in their diets than is recommended. This is alarming, as excess
dietary sodium intake expands plasma fluid volume, which may in turn attenuate the reduction
in BP following exercise. Therefore, the objective of this project is to determine the
effects of high dietary sodium intake on PEH. The investigators hypothesize that, compared to
a recommended sodium diet, a high salt diet will attenuate post-exercise hypotension.
College of Cardiology are expected to raise the prevalence of hypertension in America from
~33% to ~46%. A single bout of aerobic exercise produces a prolonged period (up to 24 hours)
of lowered blood pressure (post-exercise hypotension; PEH). Repeated bouts of aerobic
exercise results in maintenance of lowered blood pressure, leading to recommendations of
aerobic exercise for improvement of blood pressure status. However, more than 90% of
Americans consume more sodium in their diets than is recommended. This is alarming, as excess
dietary sodium intake expands plasma fluid volume, which may in turn attenuate the reduction
in BP following exercise. Therefore, the objective of this project is to determine the
effects of high dietary sodium intake on PEH. The investigators hypothesize that, compared to
a recommended sodium diet, a high salt diet will attenuate post-exercise hypotension.
Inclusion Criteria:
- Recreationally active
Exclusion Criteria:
- high blood pressure (>140/90 mmHg)
- history of cardiovascular disease
- history of cancer
- history of diabetes
- history of kidney disease
- obesity (BMI > 30 kg/m2)
- smoking or tobacco use
- current pregnancy
- nursing mothers
- communication barriers
We found this trial at
1
site
Newark, Delaware 19713
Principal Investigator: Matthew C Babcock, MS
Phone: 302-831-6178
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