COREG MR Versus TOPROL-XL On The Lipid Profile Of Normolipidemic Or Mildly Dyslipidemic Patients With Hypertension



Status:Completed
Conditions:High Blood Pressure (Hypertension)
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 80
Updated:6/27/2018
Start Date:January 5, 2006
End Date:December 28, 2007

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Trial Summary
Trial Overview
Inclusion Criteria

A Randomized, Double-Blind, Multi-Center Study Comparing the Effects of Carvedilol Phosphate Modified Release Formulation (COREG- MR) With Metoprolol Succinate (TOPROL XL) on the Lipid Profile in Normolipidemic, or Mildly Dyslipidemic Hypertensive Patients

This study was designed to determine whether treatment with COREG MR is more effective at
maintaining a better lipid profile than treatment with TOPROL-XL for hypertension.


Inclusion Criteria:

- Documented history of hypertension

- Triglycerides of 120-400 mg/mL

- LDLc levels not requiring lipid lowering medication.

Exclusion Criteria:

- Has known contraindication to alpha- or beta-blocker therapy.

- Has taken any non-ocular beta-blockers within three months before screening.

- Has Type I or II diabetes.

- Taking lipid lowering medications.
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Poway, California 92064
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Albuquerque, New Mexico 87109
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Altamonte Springs, Florida 32714
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Atlanta, Georgia 30341
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Auburn, Maine 04210
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Aurora, Illinois 60504
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Avon, Connecticut 06001
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Birmingham, Alabama 35249
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Bossier City, Louisiana 71111
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Brick, New Jersey 08723
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Bristol, Tennessee 37620
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Brooklyn Center, Minnesota 55430
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Burke, Virginia 22015
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Calgary, Alberta
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Carmichael, California 95608
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Chandler, Arizona 85224
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Charlotte, North Carolina 28203
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Chicago, Illinois 60611
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Cincinnati, Ohio 45229
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Clearwater, Florida 33759
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Cleveland, Ohio 44195
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Columbia, South Carolina 29203
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Corpus Christi, Texas 78405
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Detroit, Michigan 48202
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East Syracuse, New York 13057
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Elizabeth, New Jersey 07201
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Endwell, New York 13760
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Erie, Pennsylvania 16507
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Evansville, Indiana 47714
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Fayetteville, Arkansas 72703
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Fishkill, New York 12524
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Fort Lauderdale, Florida 33308
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Galax, Virginia 24333
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Gillespie, Illinois 62033
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Greer, South Carolina 29651
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Hartsville, South Carolina 29550
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Healdsburg, California 95448
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Henderson, Nevada 89052
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Indianapolis, Indiana 46202
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Irvine, California 92697
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Jacksonville, Florida 32207
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Kettering, Ohio 45429
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Kingsport, Tennessee 37660
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La Jolla, California 92093
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Las Vegas, Nevada 89102
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Lewisburg, West Virginia 24901
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Little Rock, Arkansas 72205
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Los Angeles, California 90025
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Manassas, Virginia 20109
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Marietta, Georgia 30060
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Mesa, Arizona 85206
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Mission Viejo, California 92691
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Montgomery, Alabama 36109
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Natick, Massachusetts 01760
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New York, New York 10032
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Newport News, Virginia 23606
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Oklahoma City, Oklahoma 73112
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Olive Branch, Mississippi 38654
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Omaha, Nebraska 68131
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Pembroke Pines, Florida 33028
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Phoenix, Arizona 85012
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Raleigh, North Carolina 27614
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Richmond, Virginia 23298
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Roswell, Georgia 30076
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Sacramento, California 95815
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Saint Louis, Missouri 63110
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Salt Lake City, Utah 84132
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San Antonio, Texas 78258
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San Diego, California 92111
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Simpsonville, South Carolina 29681
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Spring Valley, California 91978
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Springfield, Missouri 65807
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Springfield, Virginia 22151
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Statesville, North Carolina 28625
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Stockton, California 95207
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Taunton, Massachusetts 02780
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Torrance, California 90502
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Tucson, Arizona 85724
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Vernon Hills, Illinois 60061
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Virginia Beach, Virginia 23456
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Vista, California 92083
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Walla Walla, Washington 99362
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Warminster, Pennsylvania 18974
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West Chester, Pennsylvania 19380
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West Yarmouth, Massachusetts 02673
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Wichita, Kansas 67207
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Wilmington, North Carolina 28405
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Winston-Salem, North Carolina 27103
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