A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)



Status:Recruiting
Conditions:Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - Any
Updated:4/5/2019
Start Date:September 3, 2018
End Date:May 16, 2024
Contact:There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or
Email:ClinicalTrials.gov@lilly.com
Phone:1-317-615-4559

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Trial Summary
Trial Overview
Inclusion Criteria

A Multicenter, Long-Term Extension to Evaluate the Long-term Safety and Maintenance of Treatment Effect of LY3074828 in Patients With Moderate-to-Severe Plaque Psoriasis OASIS-3

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of
mirikizumab in participants with moderate-to-severe plaque psoriasis.


Inclusion Criteria:

- Participant must have completed the last visit of an eligible study period of
originating study.

- Participant must be willing to follow the birth control measures during and after
study treatment if woman of childbearing potential.

Exclusion Criteria:

- Participant must not have an unstable or uncontrolled illness, including but not
limited to a cerebro-cardiovascular, respiratory, hepatic, renal, gastrointestinal,
endocrine, hematologic, or neurologic disease or abnormal lab results, that the study
investigator thinks makes it unsafe or inappropriate for the participant to
participate in this study.

- Participant must not have stopped taking mirikizumab during a previous study if the
study investigator does not think the participant should resume taking mirikizumab.
We found this trial at
69
sites
San Luis Dermatology & Laser Clinic, Inc.
15 Santa Rosa Street
San Luis Obispo, California 93405
Principal Investigator: Michael Heffernan
Phone: 805-541-2650
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University of Alabama at Birmingham
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
Principal Investigator: Boni Elizabeth Elewski
Phone: 2055029960
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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Birmingham, AL
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Psoriasis Treatment Center of Central New Jersey
59 One Mile Road
East Windsor, New Jersey 08520
609-443-4500
Principal Investigator: Jerry Bagel
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East Windsor, NJ
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Renstar Medical Research
104 SE 1st Avenue
Ocala, Florida 34471
352-629-5800
Principal Investigator: Ashley N Bassford Cauthen
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Ocala, FL
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Oregon Health and Science University
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Principal Investigator: Alex Ortega Loayza
Phone: 503-494-4770
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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Portland, OR
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ORA Inc
Andover, Massachusetts 01810
Principal Investigator: Jeffrey M Sobell
Phone: 978-685-8900
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Andover, MA
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Austin Dermatology Associates
Austin, Texas 78705
Principal Investigator: Aron Jeffrey Gewirtzman
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Austin, TX
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Bakersfield Dermatology and Skin Cancer Medical Group
Bakersfield, California 99309
Principal Investigator: Jeffrey James Crowley
Phone: 6613273756
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Bakersfield, CA
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Louisiana Dermatology Associates
Baton Rouge, Louisiana 70806
Principal Investigator: Ira Hughes Thorla
Phone: 2259275663
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Baton Rouge, LA
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Great Lakes Research Group
Bay City, Michigan 48706
Principal Investigator: Brent Boyce
Phone: 989-895-9100
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Bay City, MI
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Bellaire Dermatology
6565 West Loop South Freeway
Bellaire, Texas 77401
Principal Investigator: Craig Teller
Phone: 832-553-2318
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Bellaire, TX
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David Stoll, MD
Beverly Hills, California 90212
Principal Investigator: David M Stoll
Phone: 310-273-6033
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Beverly Hills, CA
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Bexley Dermatology Research
Bexley, Ohio 43209
Principal Investigator: Matthew Zirwas
Phone: 614-947-1716
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Bexley, OH
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Total Skin and Beauty Dermatology Center
Birmingham, Alabama 35205
Principal Investigator: James Krell
Phone: 205-380-6148
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Birmingham, AL
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Treasure Valley Dermatology
6051 North Eagle Road
Boise, Idaho 83713
Principal Investigator: Ryan Harris
Phone: 208-467-3006
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Boise, ID
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CEDIC-Centro de Investigaciones Clinicas
Caba, Buenos Aires
Principal Investigator: Nora Noemi Kogan
Phone: 541148238701
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Caba,
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PMG Research of Cary
Cary, North Carolina 27518
Principal Investigator: Catherine Hren
Phone: 336-608-3500
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Cary, NC
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University of North Carolina Dermatology and skin Cancer Cen
410 Market Street
Chapel Hill, North Carolina 27516
Principal Investigator: Aida Lugo-Somolinos
Phone: 919-966-2485
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Chapel Hill, NC
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Dermatology and Laser Center of Charleston
Charleston, South Carolina 29414
Principal Investigator: Todd Schlesinger
Phone: 843-556-8886
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Charleston, SC
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Clarkston Skin Research
Clarkston, Michigan 48346
Principal Investigator: Wendy McFalda
Phone: 248-620-3376
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Clarkston, MI
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University Hospitals of Cleveland Medical Center
Cleveland, Ohio 44012
Principal Investigator: Neil J Korman
Phone: 216-844-3178
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Cleveland, OH
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Florida Academic Dermatology Centers
Coral Gables, Florida 33134
Principal Investigator: Francisco A Kerdel
Phone: 305-324-2110
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Coral Gables, FL
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Modern Research Associates
Dallas, Texas 75231
Principal Investigator: Jennifer A Cather
Phone: 214-361-2008
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Dallas, TX
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University Dermatology
Darien, Illinois 60561
Principal Investigator: Vassilios A Dimitropoulos
Phone: 630-920-1900
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Darien, IL
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California Dermatology and Clinical Research Institute
Encinitas, California 92024
Principal Investigator: Stacy R. Smith
Phone: 760-203-3839
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Encinitas, CA
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Dermatology and Skin Surgery Center
Exton, Pennsylvania 19341
Principal Investigator: Scott L Gottlieb
Phone: 610-594-6660
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Exton, PA
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Wright State Univ School of Medicine
3640 Colonel Glenn Highway
Fairborn, Ohio 45324
Principal Investigator: Jeffrey Travers
Phone: 937-775-2463
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Fairborn, OH
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University of Connecticut
Farmington, Connecticut 06030
Principal Investigator: Jun Lu
Phone: 860-679-4600
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Farmington, CT
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Tien Q. Nguyen, MD inc. DBA First OC Dermatology
17271 Brookhurst Street
Fountain Valley, California 92708
Principal Investigator: Vivian Laquer
Phone: 714-531-2966
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Fountain Valley, CA
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Ohio State Univ College Of Medicine
920 North Hamilton Road
Gahanna, Ohio 43230
Principal Investigator: Jessica Kaffenberger
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Gahanna, OH
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Dermatology Consulting Services
High Point, North Carolina 27262
Principal Investigator: Zoe Diana D Draelos
Phone: 336-841-2040
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High Point, NC
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Dawes Fretzin Clinical Research
Indianapolis, Indiana 46256
Principal Investigator: Scott A Fretzin
Phone: 317-621-7731
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Indianapolis, IN
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Clinical Partners, LLC
Johnston, Rhode Island 02919
Principal Investigator: Ellen H Frankel
Phone: 401-454-3800
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Johnston, RI
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Keck School of Medicine - University of Southern California
Los Angeles, California 90033
Principal Investigator: Stefani Takahashi
Phone: 323-865-3641
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Los Angeles, CA
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Dermatology Specialist
Louisville, Kentucky 40202
Principal Investigator: Cindy E Owen
Phone: 502-585-9059
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Louisville, KY
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Forefront Clinical Research
Louisville, Kentucky 40202
Principal Investigator: Mark Jackson
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Louisville, KY
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Dermatologic Surgery Specialists, Inc.
Macon, Georgia 31217
Principal Investigator: David J Cohen
Phone: 478-742-2180
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Macon, GA
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Dermatologists of Southwest Ohio, Inc.
Mason, Ohio 45040
Principal Investigator: Rocco Serrao
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Mason, OH
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International Clinical Research
Murfreesboro, Tennessee 37130
Principal Investigator: Christine Feser
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Murfreesboro, TN
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University of Utah
243 6100 South
Murray, Utah 84107
Principal Investigator: Kristina Callis-Duffin
Phone: 801-213-0375
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Murray, UT
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Mount Sinai School of Medicine Dermatology Clinical Trials
New York, New York 10029
Principal Investigator: Mark G. Lebwohl
Phone: 212-241-3288
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New York, NY
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MedaPhase, Inc.
Newnan, Georgia 30263
Principal Investigator: Mark R Ling
Phone: 770-252-6900
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Newnan, GA
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Dermatology Clinical Trials
Newport Beach, California 92660
Principal Investigator: Navid Nami
Phone: 949-720-1170
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Newport Beach, CA
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Virginia Clinical Research, Inc.
Norfolk, Virginia 23507
Principal Investigator: David M Pariser
Phone: 757-625-0151
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Norfolk, VA
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Park Avenue Dermatology
Orange Park, Florida 32073
Principal Investigator: George Schmieder
Phone: 904-458-0411
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Orange Park, FL
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Owensboro Dermatology Associates
Owensboro, Kentucky 42303
Principal Investigator: Artis P Truett
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Owensboro, KY
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Austin Institute for Clinical Research, Inc.
Pflugerville, Texas 78660
Principal Investigator: Edward Lain
Phone: 512-279-2545
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University of Pittsburgh Medical Center
200 Lothrop St
Pittsburgh, Pennsylvania 15213
Principal Investigator: Laura K Ferris
University of Pittsburgh Medical Center UPMC is one of the leading nonprofit health systems in...
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The Indiana Clinical Trials Center, PC
Plainfield, Indiana 46168
Principal Investigator: Scott T Guenthner
Phone: 317-837-6082
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Dermatology Associates Of Plymouth Meeting
Plymouth Meeting, Pennsylvania 19462
Principal Investigator: Jonathan Wolfe
Phone: 610-828-0400
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Oregon Dermatology & Research Center
Portland, Oregon 97210
Principal Investigator: Phoebe Rich
Phone: 503-226-3376
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Portland, OR
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Oregon Medical Research Center, PC
Portland, Oregon 97223
Principal Investigator: Andrew Blauvelt
Phone: 503-245-1525
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Portland, OR
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Dermatology and Skin Cancer Specialists
Rockville, Maryland 20850
Principal Investigator: Benjamin N. Lockshin
Phone: 301-355-3183
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Rockville, MD
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Lawrence J. Green, MD, LLC
Rockville, Maryland 20850
Principal Investigator: Lawrence Green
Phone: 301-610-0663
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Rockville, MD
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Arlington Dermatology
5301 Keystone Court
Rolling Meadows, Illinois 60008
Principal Investigator: Michael Bukhalo
Phone: 847-392-5440
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Rolling Meadows, IL
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Central Dermatology
Saint Louis, Missouri 63117
Principal Investigator: Craig L Leonardi
Phone: 314-721-5565
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Saint Louis, MO
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Texas Dermatology and Laser Specialists
San Antonio, Texas 78218
Principal Investigator: John C. Browning
Phone: 210-829-5180
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San Antonio, TX
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Stephen L Miller, MD, PA
San Antonio, Texas 78249
Principal Investigator: William Cragun
Phone: 210-614-2662
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San Antonio, TX
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Advanced Medical Research
Sandy Springs, Georgia 30328
Principal Investigator: Jamie Debra Weisman
Phone: 4049399220
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Sandy Springs, GA
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Clinical Science Institute
Santa Monica, California 90404
Principal Investigator: Paul S Yamauchi
Phone: 310-828-8887
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Santa Monica, CA
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Meridian Clinical Research, LLC
Savannah, Georgia 31406
Principal Investigator: Corinne Howington
Phone: 912-443-4253
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Savannah, GA
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Investigate MD
Scottsdale, Arizona 85255
Principal Investigator: Brenda LaTowsky
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Scottsdale, AZ
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DBA Dermatology Associates
Seattle, Washington 98101
Principal Investigator: Peter J Jenkin
Phone: 206-315-0377
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Seattle, WA
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South Bend Clinic
211 North Eddy St.
South Bend, Indiana 46617
574-234-8161
Principal Investigator: Holly Hake Harris
Phone: 574-204-6432
South Bend Clinic The South Bend Clinic employs a staff of 610 at its five...
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MultiCare Tacoma General Hospital
314 Martin Luther King Junior Way
Tacoma, Washington 98405
(253) 403-5200
Principal Investigator: Aaron K Pace
Phone: 253-572-2842
Multicare Health System MultiCare is a not-for-profit health care organization with more than 10,000 employees...
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Forward Clinical Trials
Tampa, Florida 33624
Principal Investigator: Seth B Forman
Phone: 813-960-2400
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Tampa, FL
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Center for Clinical Studies
Webster, Texas 77598
Principal Investigator: Patricia C. Lee
Phone: 281-333-2288
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Webster, TX
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Jordan Valley Dermatology Center
West Jordan, Utah 84088
Principal Investigator: Douglass W Forsha
Phone: 801-316-0266
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West Jordan, UT
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PMG Research of Wilmington
1907 Tradd Ct
Wilmington, North Carolina 28401
(910) 799-5500
Principal Investigator: James E Appel
Phone: 910-815-6108
PMG Research of Wilmington PMG Research of Wilmington has two offices situated in a 1...
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