A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)



Status:Recruiting
Conditions:Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - Any
Updated:4/5/2019
Start Date:September 3, 2018
End Date:May 16, 2024
Contact:There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or
Email:ClinicalTrials.gov@lilly.com
Phone:1-317-615-4559

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Trial Summary
Trial Overview
Inclusion Criteria

A Multicenter, Long-Term Extension to Evaluate the Long-term Safety and Maintenance of Treatment Effect of LY3074828 in Patients With Moderate-to-Severe Plaque Psoriasis OASIS-3

The purpose of this study is to evaluate the long-term safety and maintenance of efficacy of
mirikizumab in participants with moderate-to-severe plaque psoriasis.


Inclusion Criteria:

- Participant must have completed the last visit of an eligible study period of
originating study.

- Participant must be willing to follow the birth control measures during and after
study treatment if woman of childbearing potential.

Exclusion Criteria:

- Participant must not have an unstable or uncontrolled illness, including but not
limited to a cerebro-cardiovascular, respiratory, hepatic, renal, gastrointestinal,
endocrine, hematologic, or neurologic disease or abnormal lab results, that the study
investigator thinks makes it unsafe or inappropriate for the participant to
participate in this study.

- Participant must not have stopped taking mirikizumab during a previous study if the
study investigator does not think the participant should resume taking mirikizumab.
We found this trial at
69
sites
University of Pittsburgh Medical Center
200 Lothrop St
Pittsburgh, Pennsylvania 15213
Principal Investigator: Laura K Ferris
University of Pittsburgh Medical Center UPMC is one of the leading nonprofit health systems in...
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University of Alabama at Birmingham
1720 2nd Ave S
Birmingham, Alabama 35233
(205) 934-4011 
Principal Investigator: Boni Elizabeth Elewski
Phone: 2055029960
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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Psoriasis Treatment Center of Central New Jersey
59 One Mile Road
East Windsor, New Jersey 08520
609-443-4500
Principal Investigator: Jerry Bagel
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Renstar Medical Research
104 SE 1st Avenue
Ocala, Florida 34471
352-629-5800
Principal Investigator: Ashley N Bassford Cauthen
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Oregon Health and Science University
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Principal Investigator: Alex Ortega Loayza
Phone: 503-494-4770
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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ORA Inc
Andover, Massachusetts 01810
Principal Investigator: Jeffrey M Sobell
Phone: 978-685-8900
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Austin Dermatology Associates
Austin, Texas 78705
Principal Investigator: Aron Jeffrey Gewirtzman
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Bakersfield Dermatology and Skin Cancer Medical Group
Bakersfield, California 99309
Principal Investigator: Jeffrey James Crowley
Phone: 6613273756
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Louisiana Dermatology Associates
Baton Rouge, Louisiana 70806
Principal Investigator: Ira Hughes Thorla
Phone: 2259275663
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Great Lakes Research Group
Bay City, Michigan 48706
Principal Investigator: Brent Boyce
Phone: 989-895-9100
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Bellaire Dermatology
6565 West Loop South Freeway
Bellaire, Texas 77401
Principal Investigator: Craig Teller
Phone: 832-553-2318
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David Stoll, MD
Beverly Hills, California 90212
Principal Investigator: David M Stoll
Phone: 310-273-6033
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Bexley Dermatology Research
Bexley, Ohio 43209
Principal Investigator: Matthew Zirwas
Phone: 614-947-1716
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Total Skin and Beauty Dermatology Center
Birmingham, Alabama 35205
Principal Investigator: James Krell
Phone: 205-380-6148
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Treasure Valley Dermatology
6051 North Eagle Road
Boise, Idaho 83713
Principal Investigator: Ryan Harris
Phone: 208-467-3006
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CEDIC-Centro de Investigaciones Clinicas
Caba, Buenos Aires
Principal Investigator: Nora Noemi Kogan
Phone: 541148238701
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PMG Research of Cary
Cary, North Carolina 27518
Principal Investigator: Catherine Hren
Phone: 336-608-3500
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University of North Carolina Dermatology and skin Cancer Cen
410 Market Street
Chapel Hill, North Carolina 27516
Principal Investigator: Aida Lugo-Somolinos
Phone: 919-966-2485
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Dermatology and Laser Center of Charleston
Charleston, South Carolina 29414
Principal Investigator: Todd Schlesinger
Phone: 843-556-8886
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Clarkston Skin Research
Clarkston, Michigan 48346
Principal Investigator: Wendy McFalda
Phone: 248-620-3376
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University Hospitals of Cleveland Medical Center
Cleveland, Ohio 44012
Principal Investigator: Neil J Korman
Phone: 216-844-3178
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Florida Academic Dermatology Centers
Coral Gables, Florida 33134
Principal Investigator: Francisco A Kerdel
Phone: 305-324-2110
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Modern Research Associates
Dallas, Texas 75231
Principal Investigator: Jennifer A Cather
Phone: 214-361-2008
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University Dermatology
Darien, Illinois 60561
Principal Investigator: Vassilios A Dimitropoulos
Phone: 630-920-1900
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California Dermatology and Clinical Research Institute
Encinitas, California 92024
Principal Investigator: Stacy R. Smith
Phone: 760-203-3839
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Dermatology and Skin Surgery Center
Exton, Pennsylvania 19341
Principal Investigator: Scott L Gottlieb
Phone: 610-594-6660
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Wright State Univ School of Medicine
3640 Colonel Glenn Highway
Fairborn, Ohio 45324
Principal Investigator: Jeffrey Travers
Phone: 937-775-2463
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University of Connecticut
Farmington, Connecticut 06030
Principal Investigator: Jun Lu
Phone: 860-679-4600
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Tien Q. Nguyen, MD inc. DBA First OC Dermatology
17271 Brookhurst Street
Fountain Valley, California 92708
Principal Investigator: Vivian Laquer
Phone: 714-531-2966
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Ohio State Univ College Of Medicine
920 North Hamilton Road
Gahanna, Ohio 43230
Principal Investigator: Jessica Kaffenberger
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Dermatology Consulting Services
High Point, North Carolina 27262
Principal Investigator: Zoe Diana D Draelos
Phone: 336-841-2040
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Dawes Fretzin Clinical Research
Indianapolis, Indiana 46256
Principal Investigator: Scott A Fretzin
Phone: 317-621-7731
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Clinical Partners, LLC
Johnston, Rhode Island 02919
Principal Investigator: Ellen H Frankel
Phone: 401-454-3800
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Keck School of Medicine - University of Southern California
Los Angeles, California 90033
Principal Investigator: Stefani Takahashi
Phone: 323-865-3641
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Dermatology Specialist
Louisville, Kentucky 40202
Principal Investigator: Cindy E Owen
Phone: 502-585-9059
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Louisville, KY
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Forefront Clinical Research
Louisville, Kentucky 40202
Principal Investigator: Mark Jackson
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Dermatologic Surgery Specialists, Inc.
Macon, Georgia 31217
Principal Investigator: David J Cohen
Phone: 478-742-2180
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Dermatologists of Southwest Ohio, Inc.
Mason, Ohio 45040
Principal Investigator: Rocco Serrao
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International Clinical Research
Murfreesboro, Tennessee 37130
Principal Investigator: Christine Feser
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University of Utah
243 6100 South
Murray, Utah 84107
Principal Investigator: Kristina Callis-Duffin
Phone: 801-213-0375
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Mount Sinai School of Medicine Dermatology Clinical Trials
New York, New York 10029
Principal Investigator: Mark G. Lebwohl
Phone: 212-241-3288
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MedaPhase, Inc.
Newnan, Georgia 30263
Principal Investigator: Mark R Ling
Phone: 770-252-6900
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Newnan, GA
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Dermatology Clinical Trials
Newport Beach, California 92660
Principal Investigator: Navid Nami
Phone: 949-720-1170
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Virginia Clinical Research, Inc.
Norfolk, Virginia 23507
Principal Investigator: David M Pariser
Phone: 757-625-0151
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Park Avenue Dermatology
Orange Park, Florida 32073
Principal Investigator: George Schmieder
Phone: 904-458-0411
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Owensboro Dermatology Associates
Owensboro, Kentucky 42303
Principal Investigator: Artis P Truett
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Austin Institute for Clinical Research, Inc.
Pflugerville, Texas 78660
Principal Investigator: Edward Lain
Phone: 512-279-2545
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The Indiana Clinical Trials Center, PC
Plainfield, Indiana 46168
Principal Investigator: Scott T Guenthner
Phone: 317-837-6082
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Dermatology Associates Of Plymouth Meeting
Plymouth Meeting, Pennsylvania 19462
Principal Investigator: Jonathan Wolfe
Phone: 610-828-0400
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Oregon Dermatology & Research Center
Portland, Oregon 97210
Principal Investigator: Phoebe Rich
Phone: 503-226-3376
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Oregon Medical Research Center, PC
Portland, Oregon 97223
Principal Investigator: Andrew Blauvelt
Phone: 503-245-1525
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Dermatology and Skin Cancer Specialists
Rockville, Maryland 20850
Principal Investigator: Benjamin N. Lockshin
Phone: 301-355-3183
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Lawrence J. Green, MD, LLC
Rockville, Maryland 20850
Principal Investigator: Lawrence Green
Phone: 301-610-0663
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Arlington Dermatology
5301 Keystone Court
Rolling Meadows, Illinois 60008
Principal Investigator: Michael Bukhalo
Phone: 847-392-5440
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Central Dermatology
Saint Louis, Missouri 63117
Principal Investigator: Craig L Leonardi
Phone: 314-721-5565
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Texas Dermatology and Laser Specialists
San Antonio, Texas 78218
Principal Investigator: John C. Browning
Phone: 210-829-5180
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Stephen L Miller, MD, PA
San Antonio, Texas 78249
Principal Investigator: William Cragun
Phone: 210-614-2662
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San Luis Dermatology & Laser Clinic, Inc.
15 Santa Rosa Street
San Luis Obispo, California 93405
Principal Investigator: Michael Heffernan
Phone: 805-541-2650
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Advanced Medical Research
Sandy Springs, Georgia 30328
Principal Investigator: Jamie Debra Weisman
Phone: 4049399220
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Clinical Science Institute
Santa Monica, California 90404
Principal Investigator: Paul S Yamauchi
Phone: 310-828-8887
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Meridian Clinical Research, LLC
Savannah, Georgia 31406
Principal Investigator: Corinne Howington
Phone: 912-443-4253
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Savannah, GA
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Investigate MD
Scottsdale, Arizona 85255
Principal Investigator: Brenda LaTowsky
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DBA Dermatology Associates
Seattle, Washington 98101
Principal Investigator: Peter J Jenkin
Phone: 206-315-0377
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South Bend Clinic
211 North Eddy St.
South Bend, Indiana 46617
574-234-8161
Principal Investigator: Holly Hake Harris
Phone: 574-204-6432
South Bend Clinic The South Bend Clinic employs a staff of 610 at its five...
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MultiCare Tacoma General Hospital
314 Martin Luther King Junior Way
Tacoma, Washington 98405
(253) 403-5200
Principal Investigator: Aaron K Pace
Phone: 253-572-2842
Multicare Health System MultiCare is a not-for-profit health care organization with more than 10,000 employees...
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Forward Clinical Trials
Tampa, Florida 33624
Principal Investigator: Seth B Forman
Phone: 813-960-2400
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Center for Clinical Studies
Webster, Texas 77598
Principal Investigator: Patricia C. Lee
Phone: 281-333-2288
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Jordan Valley Dermatology Center
West Jordan, Utah 84088
Principal Investigator: Douglass W Forsha
Phone: 801-316-0266
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PMG Research of Wilmington
1907 Tradd Ct
Wilmington, North Carolina 28401
(910) 799-5500
Principal Investigator: James E Appel
Phone: 910-815-6108
PMG Research of Wilmington PMG Research of Wilmington has two offices situated in a 1...
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