Effect of Transcranial Direct Current Stimulation on Peripheral Neuropathy
| Status: | Recruiting |
|---|---|
| Conditions: | Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 11/8/2018 |
| Start Date: | March 2016 |
| End Date: | March 2019 |
| Contact: | Mohammad Khoshnoodi, MD |
| Phone: | 410-955-5406 |
Effect of Transcranial Direct Current Stimulation on Proprioceptive and Vibratory Sensation: Potential Benefit for Patients With Peripheral Neuropathy
This study will be performed in patients with peripheral neuropathy who are walking
independently, but have complains of balance problems such as recent falls or difficulty
walking and show reduced vibratory and proprioceptive sensation during routine neurologic
examination. These patients will be tested for proprioceptive and vibratory threshold at the
toes and ankles before, during and after receiving anodal direct transcranial cortical
stimulation (dTCS) over sensory and motor cortices. Subjects will be asked to participate in
2 sessions.
independently, but have complains of balance problems such as recent falls or difficulty
walking and show reduced vibratory and proprioceptive sensation during routine neurologic
examination. These patients will be tested for proprioceptive and vibratory threshold at the
toes and ankles before, during and after receiving anodal direct transcranial cortical
stimulation (dTCS) over sensory and motor cortices. Subjects will be asked to participate in
2 sessions.
This study will be performed in patients with peripheral neuropathy who are walking
independently, but have complains of balance problems such as recent falls or difficulty
walking and show reduced vibratory and proprioceptive sensation during routine neurologic
examination. These patients will be tested for proprioceptive and vibratory threshold at the
toes and ankles before, during and after receiving anodal transcranial direct current
stimulation (tDCS) over sensory and motor cortices. Subjects will be asked to participate in
2 sessions. In one of the sessions, decided randomly, the stimulation will be applied on the
right side and in the second session it will be on the left.
The tDCS portion of the experiment will begins with direct current (maximum of 2 mA)
stimulation delivered through surface electrodes (TransQE from IOMED®, surface area: 25 cm2)
using a Phoresor® II Auto (Model No. PM850, IOMED®, Salt Lake City, Utah 84120, USA). One
electrode will be positioned above the left or right primary motor cortex, the other
electrode over the forehead.
independently, but have complains of balance problems such as recent falls or difficulty
walking and show reduced vibratory and proprioceptive sensation during routine neurologic
examination. These patients will be tested for proprioceptive and vibratory threshold at the
toes and ankles before, during and after receiving anodal transcranial direct current
stimulation (tDCS) over sensory and motor cortices. Subjects will be asked to participate in
2 sessions. In one of the sessions, decided randomly, the stimulation will be applied on the
right side and in the second session it will be on the left.
The tDCS portion of the experiment will begins with direct current (maximum of 2 mA)
stimulation delivered through surface electrodes (TransQE from IOMED®, surface area: 25 cm2)
using a Phoresor® II Auto (Model No. PM850, IOMED®, Salt Lake City, Utah 84120, USA). One
electrode will be positioned above the left or right primary motor cortex, the other
electrode over the forehead.
Inclusion Criteria:
- Peripheral Neuropathy
- Walking independently but with problems with balance
Exclusion Criteria:
- Prominent weakness at the ankle
- Not able to walk independently
- History of Seizure
- Cardiac Pacemaker
- Metal implants in the head
- Increased intracranial pressure
- Pregnancy
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