Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation



Status:Completed
Conditions:Atrial Fibrillation, Atrial Fibrillation
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:Any
Updated:7/5/2018
Start Date:December 31, 2006
End Date:May 25, 2011

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase 3, Active (Warfarin) Controlled, Randomized, Double-Blind, Parallel Arm Study to Evaluate Efficacy and Safety of Apixaban in Preventing Stroke and Systemic Embolism in Subjects With Nonvalvular Atrial Fibrillation

The trial seeks to determine if apixaban, an investigational anticoagulant (blood-thinner) is
as effective as standard therapy (warfarin) in preventing stroke and systemic embolism in
subjects with atrial fibrillation and risk factors for stroke.


Inclusion Criteria:

- Males and females ≥ 18 yrs with atrial fibrillation (AF) and one or more of the
following risk factors for stroke:

- Age ≥ 75, previous stroke

- transient ischemic attack (TIA) or Systemic Embolism (SE)

- Symptomatic congestive heart failure or left ventricular dysfunction with left
ventricular ejection fraction (LVEF) ≤ 40%

- Diabetes mellitus or hypertension requiring pharmacological treatment
We found this trial at
262
sites
Johns Hopkins Bayview Medical Center
4940 Eastern Ave
Baltimore, Maryland 21224
(410) 550-0100
Johns Hopkins Bayview Medical Center There is no better story in American medicine in the...
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Comprehensive Clinical Research
175 Cross Keys Rd.
Berlin, New Jersey 08009
856-753-7335
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Berlin, NJ
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The Heart & Vascular Institute Of Florida
455 Pinellas St., Suite 330
Clearwater, Florida 33756
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HealthwoRx
3702 Washington Street
Hollywood, Florida 33021
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Jacksonville Center for Clinical Research
4085 University Blvd S # 1
Jacksonville, Florida 32216
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Jacksonville Heart Center, PA
1361 13th Ave S # 270
Jacksonville Beach, Florida 32250
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DCOL Center for Clinical Research
707 Hollybrook Drive
Longview, Texas 75605
903-238-8854
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Melbourne Internal Medicine Associates
Melbourne, Florida
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Univ of Minnesota
Minneapolis, Minnesota 55455
(612) 625-5000
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The William W. Backus Hospital
326 Washington Street
Norwich, Connecticut 06360
860-892-6936
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Rhode Island Hospital
593 Eddy Street
Providence, Rhode Island 02903
401-444-4000
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
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Castlerock Clinical Research Consultants, LLC
6804 South Canton
Tulsa, Oklahoma 74136
918-524-5205
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Chase Medical Research, LLC
500 Chase Parkway
Waterbury, Connecticut 06708
203-419-4420
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Abington Medical Specialists
Abington, Pennsylvania 19001
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Local Institution
Adrogue, Buenos Aires
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Akron Cardiology Consultants
Akron, Ohio 44304
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Albany Assoc. In Cardiology
Albany, New York 12205
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Albany Associates in Cardiology
Albany, New York 12212
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Abq Health Partners, Llc
Albuquerque, New Mexico 87012
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University Of New Mexico/University Hospital
Albuquerque, New Mexico 87131
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Alexandria Cardiology Clinic
Alexandria, Louisiana 71301
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Great Lakes Heart Center Of Alpena
Alpena, Michigan 49707
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Blair Medical Associates Inc.
Altoona, Pennsylvania 16602
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Amarillo Heart Clinical Research Institute Inc.
Amarillo, Texas 79106
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McFarland Clinic, PC
Ames, Iowa 50010
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Advanced Clinical Reserach Institute
Anaheim, California 92801
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Alaska Heart Institute
Anchorage, Alaska 99508
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Community Clinical Research Center
Anderson, Indiana 46011
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Southeastern Research Associates, Inc
Anderson, South Carolina 29621
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Asheville Cardiology Associates
Asheville, North Carolina 28802
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Cardiovascular Specialits, Pc
Atlanta, Georgia 30342
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Medical Specialist Of The Palm Beach
Atlantis, Florida 33462
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Augusta Cardiology Clinic, P.C.
Augusta, Georgia 30901
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Fox Valley Clinical Research Center, LLC
Aurora, Illinois 60504
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Miami International Cardiology Consultants
Aventura, Florida 33180
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Midatlantic Cardiovascular Associates
Baltimore, Maryland 21204
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Franklin Square Hospital
Baltimore, Maryland 21237
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Lowcountry Medical Group, Llc
Beaufort, South Carolina 29906
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Midatlantic Cardiovascular Associates PA
Bel Air, Maryland 21014
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St. Charles Health System
Bend, Oregon 97701
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Act/Cardiovascular Research Institute
Beverly Hills, California 90210
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Burlington Medical Associates
Billerica, Massachusetts 01821
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Cardiology Associates, Pc
Binghamton, New York 13905
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Cardiovascular Associates
Birmingham, Alabama 35213
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Alabama Internal Medicine, PC
Birmingham, Alabama 35235
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Birmingham Heart Clinic
Birmingham, Alabama 35235
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Premier Healthcare
Bloomington, Indiana 47403
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David Charles Mishkel, Md, Pa
Boca Raton, Florida 33431
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Caritas St. Elizabeth's Medical Center
Boston, Massachusetts 02190
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Connecticut Clinical Research, LLC
Bridgeport, Connecticut 06606
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Bridgeport Hospital
Bridgeport, Connecticut 06610
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Holston Medical Group
Bristol, Tennessee 37620
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Christopher M. Johnson, D.O.
Bucyrus, Ohio 44820
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Buffalo Heart Group LLP
Buffalo, New York 14215
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Bruce L. Platt Md, Pc
Buffalo, New York 14215
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Daniel W. Gottlieb, Md, Ps
Burien, Washington 98166
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Daniel William Gottlieb, Md
Burien, Washington 98166
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Lahey Clinic Medical Center
Burlington, Massachusetts 01805
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Kernodle Clinic, Inc.
Burlington, North Carolina 27215
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Heritage Cardiology Assoc.
Camp Hill, Pennsylvania 17011
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Community Health Care, Inc.
Canal Fulton, Ohio 44614
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Cardiology Associates
Canton, Ohio 44710
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Capitol Interventional Cardiology
Carmichael, California 95608
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Medical University of South Carolina
171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
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Nmff
Chicago, Illinois 60611
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The Carl & Edyth Lindner Center For R&E At The Christ Hosp
Cincinnati, Ohio 45219
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Electrophysiology Associates, Pc
Colorado Springs, Colorado 80910
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Cardiovascular Specialists of Central Maryland
10710 Charter Drive
Columbia, Maryland 21044
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University of Missouri
Columbia, Missouri 65211
(573) 882-2121
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Columbia Heart Clinic
Columbia, South Carolina 29203
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Columbus Cardiology Associates, PC
Columbus, Georgia 31909
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Corsicana Medical Research
Corsicana, Texas 75110
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Georgia Heart Specialists
Covington, Georgia 30014
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Soltero Cardiovascular Research Center
Dallas, Texas 75226
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Heartplace
621 Hall Street
Dallas, Texas 75226
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Cardiovascular Specialist Of South Florida
Davie, Florida 33324
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Daytona Heart Group
Daytona Beach, Florida 32114
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Atlanta Institute for Medical Research, Inc
Decatur, Georgia 30030
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Aurora Denver Cardiology Associates
Denver, Colorado 80218
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Denver VA Medical Center
Denver, Colorado 80220
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Henry Ford Hospital
2799 W Grand Blvd
Detroit, Michigan 48202
(313) 916-2600
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Central Bucks Cardiology
Doylestown, Pennsylvania 18901
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Heart Care Center
4939 Brittonfield Parkway
East Syracuse, New York 13057
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Central Cardiology Assoc.
Elizabethtown, Kentucky 42701
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Elkhart Clinic, LLC
303 S Nappanee St
Elkhart, Indiana 46514
(574) 296-3200
Elkhart Clinic, LLC Informed participation in the management of your health care maximizes your Elkhart...
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Cardiovascular Associates Of The Delware Valley, P.A.
Elmer, New Jersey 08318
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Internal Medicine And Lipid Mgmt.
Erie, Pennsylvania 16509
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Escondido Cardiology Associates, Inc.
Escondido, California 92025
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Oregon Medical Group Clinical Research
Eugene, Oregon 97401
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NECCR Internal Medicine & Cardiology Associates, LLC
Fall River, Massachusetts 02720
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Lillestol Research LLC
Fargo, North Dakota 58103
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Cardiology Associates Of Fort Lauderdale, P.A.
Fort Lauderdale, Florida 33308
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Broward General Medical Center
Fort Lauderdale, Florida 33316
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Florida Heart Associates
Fort Myers, Florida 33907
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Lutheran Medical Group, LLC
Fort Wayne, Indiana 46804
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Fort Wayne Cardiology
Fort Wayne, Indiana 46805
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Heart Center of North Texas
Fort Worth, Texas 76104
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Florida Research Network
Gainesville, Florida 32605
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Northeast Georgia Heart Center
Gainesville, Georgia
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New West Physicians Clinical Research
Golden, Colorado 80401
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Internal Medical Associates Of Grand Island, P.C
Grand Island, Nebraska 68803
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