A Study to Assess if Mirikizumab is Effective and Safe Compared to Secukinumab and Placebo in Moderate to Severe Plaque Psoriasis (OASIS-2)
| Status: | Recruiting |
|---|---|
| Conditions: | Psoriasis |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/5/2019 |
| Start Date: | June 26, 2018 |
| End Date: | December 11, 2020 |
| Contact: | There may be multiple sites in this clinical trial. 1-877-CTLILLY |
| Email: | ClinicalTrials.gov@lilly.com |
| Phone: | 1-317-615-4559 |
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Comparing the Efficacy and Safety of Mirikizumab to Secukinumab and Placebo in Patients With Moderate-to-Severe Plaque Psoriasis OASIS-2
The reason for this study is to see how effective and safe mirikizumab is compared to
secukinumab and placebo for moderate to severe plaque psoriasis.
secukinumab and placebo for moderate to severe plaque psoriasis.
Inclusion Criteria:
- Participant must have chronic plaque psoriasis for at least 6 months.
Exclusion Criteria:
- Participant must not be breastfeeding or nursing woman.
- Participant must not have had serious, opportunistic, or chronic/recurring infection
within 3 months.
- Participant must not have received a Bacillus Calmette-Guerin (BCG) vaccination within
12 months or received live vaccine(s) (including attenuated live vaccines) within 12
weeks of baseline or intend to receive either during the study.
- Participant must not have any other skin conditions (excluding psoriasis).
- Participant must not have previous exposure to Cosentyx and any other biologic therapy
targeting IL-17 (including Taltz).
- Participant must not have received anti-tumor necrosis factor (TNF) biologics within 8
weeks.
- Participant must not have previous exposure to any biologic therapy targeting IL-23
(including Stelara).
We found this trial at
48
sites
Dallas, Texas 75231
Principal Investigator: Jennifer A Cather
Phone: 214-361-2008
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1720 2nd Ave S
Birmingham, Alabama 35233
Birmingham, Alabama 35233
(205) 934-4011
Principal Investigator: Boni Elizabeth Elewski
Phone: 2055029960
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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59 One Mile Road
East Windsor, New Jersey 08520
East Windsor, New Jersey 08520
609-443-4500
Principal Investigator: Jerry Bagel
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
Principal Investigator: Alex Ortega Loayza
Phone: 503-494-4770
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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Austin, Texas 78660
Principal Investigator: Aron Jeffrey Gewirtzman
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Bakersfield, California 99309
Principal Investigator: Jeffrey James Crowley
Phone: 6613273756
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Baton Rouge, Louisiana 70806
Principal Investigator: Ira Hughes Thorla
Phone: 2259275663
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Beverly Hills, California 90212
Principal Investigator: David M Stoll
Phone: 310-273-6033
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Bexley, Ohio 43209
Principal Investigator: Matthew Zirwas
Phone: 614-725-1716
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6051 North Eagle Road
Boise, Idaho 83713
Boise, Idaho 83713
Principal Investigator: Ryan Harris
Phone: 208-467-3006
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Caba, Buenos Aires
Principal Investigator: Nora Noemi Kogan
Phone: 541148238701
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Cary, North Carolina 27518
Principal Investigator: Catherine Hren
Phone: 919-342-3447
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410 Market Street
Chapel Hill, North Carolina 27516
Chapel Hill, North Carolina 27516
Principal Investigator: Aida Lugo-Somolinos
Phone: 984-974-3672
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Cleveland, Ohio 44012
Principal Investigator: Neil J Korman
Phone: 216-844-3178
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Darien, Illinois 60561
Principal Investigator: Vassilios A Dimitropoulos
Phone: 630-920-1900
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Encinitas, California 92024
Principal Investigator: Stacy R. Smith
Phone: 760-203-3839
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725 University Boulevard
Fairborn, Ohio 45324
Fairborn, Ohio 45324
Principal Investigator: Jeffrey Travers
Phone: 937-775-2463
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17271 Brookhurst Street
Fountain Valley, California 92708
Fountain Valley, California 92708
Principal Investigator: Vivian Laquer
Phone: 714-531-2966
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Indianapolis, Indiana 46256
Principal Investigator: Scott A Fretzin
Phone: 317-621-7731
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Johnston, Rhode Island 02919
Principal Investigator: Ellen H Frankel
Phone: 401-454-3800
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Los Angeles, California 90033
Principal Investigator: Stefani Takahashi
Phone: 323-865-3641
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Louisville, Kentucky 40202
Principal Investigator: Cindy E Owen
Phone: 502-585-9059
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Macon, Georgia 31217
Principal Investigator: David J Cohen
Phone: 478-742-2180
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New York, New York 10029
Principal Investigator: Mark G. Lebwohl
Phone: 212-241-3288
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Newport Beach, California 92660
Principal Investigator: Navid Nami
Phone: 949-720-1170
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Norfolk, Virginia 23507
Principal Investigator: David M Pariser
Phone: 757-622-6315
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Orange Park, Florida 32073
Principal Investigator: George Schmieder
Phone: 904-458-0411
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Pflugerville, Texas 78660
Principal Investigator: Edward Lain
Phone: 512-279-2545
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Plainfield, Indiana 46168
Principal Investigator: Scott T Guenthner
Phone: 317-837-6082
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Portland, Oregon 97210
Principal Investigator: Phoebe Rich
Phone: 503-226-3376
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Rockville, Maryland 20850
Principal Investigator: Benjamin N. Lockshin
Phone: 301-355-3183
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Rockville, Maryland 20850
Principal Investigator: Lawrence Green
Phone: 301-610-0663
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5301 Keystone Court
Rolling Meadows, Illinois 60008
Rolling Meadows, Illinois 60008
Principal Investigator: Michael Bukhalo
Phone: 847-392-5440
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Saint Louis, Missouri 63117
Principal Investigator: Craig L Leonardi
Phone: 314-721-5565
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San Antonio, Texas 78218
Principal Investigator: John C. Browning
Phone: 210-829-5180
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San Antonio, Texas 78249
Principal Investigator: William Cragun
Phone: 210-614-2662
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15 Santa Rosa Street
San Luis Obispo, California 93405
San Luis Obispo, California 93405
Principal Investigator: Michael Heffernan
Phone: 805-541-2650
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Santa Monica, California 90404
Principal Investigator: Paul S Yamauchi
Phone: 310-828-8887
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Savannah, Georgia 31406
Principal Investigator: Corinne Howington
Phone: 912-443-4253
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Seattle, Washington 98101
Principal Investigator: Peter J Jenkin
Phone: 206-315-0377
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211 North Eddy St.
South Bend, Indiana 46617
South Bend, Indiana 46617
574-234-8161
Principal Investigator: Holly Hake Harris
Phone: 574-204-6432
South Bend Clinic The South Bend Clinic employs a staff of 610 at its five...
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Webster, Texas 77598
Principal Investigator: Patricia C. Lee
Phone: 281-333-2288
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West Jordan, Utah 84088
Principal Investigator: Douglass W Forsha
Phone: 801-316-0266
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1907 Tradd Ct
Wilmington, North Carolina 28401
Wilmington, North Carolina 28401
(910) 799-5500
Principal Investigator: James E Appel
Phone: 910-799-5500
PMG Research of Wilmington PMG Research of Wilmington has two offices situated in a 1...
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