Central Auditory Processing Disorders Associated With Blast Exposure



Status:Completed
Conditions:Cognitive Studies, Other Indications, Other Indications, Neurology, Neurology
Therapuetic Areas:Neurology, Psychiatry / Psychology, Other
Healthy:No
Age Range:18 - Any
Updated:8/12/2018
Start Date:October 2007
End Date:December 2011

Use our guide to learn which trials are right for you!

The incidence of central auditory dysfunction in war fighters who are exposed to
high-explosive blasts while serving in combat have not been clearly determined. The
objectives of this study are to determine whether central auditory processing (CAP) disorders
are associated with exposure to high-explosive blasts. This study will also examine the
incidence, magnitude and timing of spontaneous recovery of CAP function from blast exposure.
The information provided by this study will help guide clinicians in both the military and VA
health care systems regarding the likelihood of central auditory processing disorders in
soldiers returning from deployment and suggest some clinical rehabilitative strategies for
the treatment of these patients with CAP deficits.

The incidence and nature of central auditory dysfunction in combat soldiers who are exposed
to high-explosive blasts have not been determined. Using a battery of behavioral and
neurophysiological auditory tests, we propose to evaluate central auditory function in
soldiers who recently have been exposed to explosive blasts while deployed in Iraq or
Afghanistan. In collaboration with the Army Audiology & Speech Center at Walter Reed Army
Medical Center (WRAMC), the research will be coordinated at the National Center for
Rehabilitative Auditory Research (NCRAR) at the Portland VA Medical Center, and data
collection will take place both at the NCRAR and at WRAMC. The study objectives are to
determine if specific central auditory processing disorders are often associated with
exposure to high-explosive blasts, and if these disorders spontaneously recover or remain
over time. One hundred patients who have suffered a blast exposure, but have either no brain
damage or mild traumatic brain injury (TBI), will be recruited at WRAMC to participate in
this research study. A battery of central auditory processing tests will be administered to
participants as soon as possible after their arrival at WRAMC. Patients who demonstrate
aspects of central auditory processing disorder will be invited to participate in further
testing nine to twelve months later. Those subjects will be brought to the NCRAR at the
Portland VA Medical Center or will return to WRAMC for two days of auditory testing, where
they will undergo the same battery of tests administered initially. Control subjects who do
not have a history of blast exposure and who are matched in age, gender, and audiometric
configuration with the experimental subjects will also be tested at the NCRAR site. Data
extracted by interview and from medical records, including details of the blast exposure,
scores on overall tests of brain function administered by the WRAMC TBI team, presence or
absence of post traumatic stress disorder, as well as self-report questionnaires regarding
quality of life, presence of tinnitus and/or balance problems, will be used in the
interpretation of results.

Inclusion Criteria:

Experimental group:

- Active duty soldier at Walter Reed Army Medical Center, Washington DC

- a notation in medical record of exposure to blast

- a Glasgow Coma Scale of 13-15, indicating mild or no traumatic brain injury (TBI

- cognitive and physical ability to take part in these auditory evaluations.

- Age 18 years or older

- native speaker of English (since test materials are presented in English)

Control group:

- able to commute to Portland (Oregon)VA Med Ctr.

- no exposure to blast

- cognitive and physical ability to take part in these auditory evaluations.

- age 18 years or older

- native speaker of English

Exclusion Criteria:

- hearing loss greater than 50 dB HL three-frequency pure tone average bilaterally
We found this trial at
1
site
6900 Georgia Ave NW
Washington, District of Columbia 20307
(202) 782-6849
Walter Reed Army Medical Center The Walter Reed National Military Medical Center is one of...
?
mi
from
Washington,
Click here to add this to my saved trials