Influence of Mango Intake of Skin Health in Postmenopausal Women



Status:Recruiting
Healthy:No
Age Range:50 - 70
Updated:9/5/2018
Start Date:July 17, 2018
End Date:December 30, 2019
Contact:Vivien Fam
Email:wfam@ucdavis.edu
Phone:530-760-5968

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Influence of Mango Intake on Skin Health in Postmenopausal Women

This study aims to investigate the effects on 16 weeks of mango intake on skin health in
postmenopausal women. Half of the participants will receive 85g portions of mangoes while the
other half receive 250g portions of mangos. Participants will be instructed to consume the
specific portion 4 times a week, for a total duration of 16 weeks.

Mangoes are rich in carotenoids, flavonoids, vitamins and other active phytochemicals such as
resistant starches. Although a role of mangoes in skin health has long been advocated in
traditional medicine, little scientific research has been conducted.

We hypothesize that 85g (0.5 cups) of mango intake for 16 weeks will have minimal impact on
skin health, while 250g (1.5 cups) of mango intake will produce significant benefits.

Inclusion Criteria:

- Postmenopausal

- Fitzpatrick skin type I and II

- BMI 18.5 - 35.0 kg/m2

- Normal blood levels in the comprehensive metabolic panel, or values slightly out of
range as approved by the study physician

Exclusion Criteria:

- Allergic to mangoes

- Fruit consumption of 2 or more cups per day

- Vegetable consumption of 3 or more cups per day for females

- Fruit juice consumption of more than 1 cup per day

- Self-reported malabsorption

- Currently taking regular prescription drugs i.e. statins, thyroid, anti-inflammatory
drugs

- Had any medical or cosmetic procedures such as laser resurfacing or plastic surgery to
the face within the last 6 months, including botulinum toxin, dermal fillers, collagen
or other similar cosmetic procedure

- Autoimmune photosensitive condition or known genetic condition with a deficiency in
collagen production (such as Ehler-Danlos)

- Smoking (current smoker, smoked within the past year, former smokers with greater than
a 20 pack-year history of smoking within the past 20 years.

- Indications of substance or alcohol abuse

- Unwillingness to discontinue high antioxidant supplements during washout and
interventions
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Davis, California 95616
Phone: 530-752-7620
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