Effects of a Weight Loss Intervention in College-age Women

The purpose of this study is three-fold: 1) Determine whether an 8-week, patient-centered,
weight loss intervention can be successfully implemented in overweight, college-age females
for promotion of weight loss and prevention of weight regain at 8-weeks, three months, and
six months follow-up; 2) Determine the effects of the intervention on established markers of
calorie restriction, energy expenditure and body composition; 3) Determine the effects of a
liquid meal on physiological and subjective markers of hunger and satiety from pre- to post-
8wk intervention in the intervention group vs control group.

Inclusion Criteria:

- Females age 18-25years

- Body Mass Index 25.0 to 29.9 kg/m2 (overweight)

- Agree to receive frequent contacts from investigators and communicate with program
staff for up to 6 months

- Willing to measure blood glucose via finger prick test three to eight times per day
for two weeks

- Able to give written informed consent

- Able to comply with study procedures

Exclusion Criteria:

- Unable or unwilling to give informed consent

- Travel plans that do not permit participation

- Pregnant or planning on becoming pregnant during the 6 months of participation in the
study

- Weight loss or gain exceeding 5% of body weight in the past 3 months

- Current participation in a weight loss program

- Diagnosis of mental disorder or chronic disease

- History of eating disorder such as anorexia nervosa, bulimia nervosa, or binge eating
disorder (unless approved by program staff)

- History of surgery or procedure that could affect swallowing or digestion

- Any person who is on a medically prescribed diet

- Any current supplement use other than a daily multivitamin

- Any current metabolic medication use other than birth control

- Any bleeding disorders or blood clotting problems

- Anyone who has donated blood or plasma in the last 20 days

- Any tobacco or illicit drug users

- Anyone who has allergies to any of the components of the liquid meal