The STOP-HPV Trial 6: Single Arm Evaluation of the Maintenance of the STOP-HPV Bundle

HPV vaccine rates remain lower than rates for other adolescent vaccines. Missed opportunities
(MOs) are healthcare visits during which a patient is eligible, but does not receive a
vaccine. MOs for vaccination contribute strongly to low HPV vaccination rates. This single
arm evaluation (embedded within arm 1 of a 2-arm cluster RCT) will test the sustainability of
improvement made in repose to a bundled intervention including HPV vaccine communication
(done through online educational modules and live office practice sessions), performance
feedback reports (that pull from electronic health record (EHR) data, and compare
participants performance to their own previous performance and those of others) and provider
prompts (via EHR and also office staff prompts, e.g., placing Vaccine Information Statements
(VISs) on desk) to reduce MOs and increase HPV vaccination rates.

Practice Inclusion Criteria:

- The practice provides HPV vaccination services to adolescents.

- The practice is part of Physician's Computer Company (PCC), Office Practicum (OP) or
(a) yet-to-be selected health system(s).

- The practice has had the same EHR system in place for a year or more (with special
consideration on a case by case basis if they are close to but not do not reach a
year).

- The practice agrees to not participate in other HPV-related QI projects or research
interventions during the study period (with special consideration on a case by case
basis).

Practice Exclusion Criteria:

- The practice plans to change EHR systems in the next three years.

- The practice participated in the last year, is currently engaged in, or plans to
participate in an office-based HPV-related quality improvement (QI) project or
research intervention during the study period (with special consideration on a case by
case basis).

- Estimated 20% or more of adolescents at the practice receive HPV vaccinations at
schools or health department clinics (given standard practice and published data, the
investigators expect that few to no practices will need to be excluded based on this
restriction).

Patient inclusion criteria:

-All patients of participating practices (intervention and comparison) aged 11-17 years who
have at least 1 visit to the practice within the past two years.

Patient exclusion criteria:

-None apart from age of patients (above).