Mupirocin-Iodophor ICU Decolonization Swap Out Trial



Status:Recruiting
Conditions:Infectious Disease
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:Any
Updated:8/8/2018
Start Date:May 1, 2017
End Date:December 2023
Contact:Katie Haffenreffer
Email:Katie_Haffenreffer@hphc.org
Phone:617-867-4807

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

Cluster-randomized Non-inferiority Trial Comparing Mupirocin vs Iodophor for Nasal Decolonization of ICU Patients to Assess Impact on S. Aureus Clinical Cultures and All-cause Bloodstream Infection During Routine Chlorhexidine Bathing

The Swap Out Trial is a cluster randomized controlled trial of HCA hospitals, evaluating the
non-inferiority of two decolonization regimens:

Arm 1 Routine Care: ICU nasal decolonization with mupirocin twice daily for 5 days in the
context of chlorhexidine for daily bathing; Arm 2 Intervention: ICU nasal decolonization with
iodophor twice daily for 5 days in the context of chlorhexidine for daily bathing Note: that
enrolled "subjects" represents 137 individual HCA Hospitals (representing ~235 ICUs) that
have been randomized.


Inclusion Criteria:

- Inclusion criteria includes all U.S. HCA hospitals with an adult ICU;

- Note: Unit of randomization is the hospital, but the participants are hospital adult
ICUs

- All patients within adult ICUs are included, including rare patients <18 years and
>=12 years.

Exclusion Criteria:

- Exclusion criteria includes ICUs with an average length of stay of less than 2 days;

- HCA hospitals that are not able to transfer or merge data into the centralized data
warehouse for the baseline and intervention periods of the study are also excluded.
We found this trial at
137
sites
Capital Regional Medical Center
Tallahassee, Florida 32308
?
mi
from
Tallahassee, FL
Click here to add this to my saved trials
Medical City Dallas Hospital
7777 Forest Ln # C840
Dallas, Texas 75230
(972) 566-7000
Medical City Dallas Hospital If you have concerns for your health, that of a family...
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Presbyterian - St. Luke's Medical Center
1719 East 19th Avenue
Denver, Colorado 80218
(303) 839-6000
Presbyterian - St. Luke's Medical Center Presbyterian/St. Luke's Medical Center and the Rocky Mountain Hospital...
?
mi
from
Denver, CO
Click here to add this to my saved trials
Rapides Regional Medical Center
211 4th Street
Alexandria, Louisiana 71301
?
mi
from
Alexandria, LA
Click here to add this to my saved trials
Medical Center of Arlington
Arlington, Texas 76015
?
mi
from
Arlington, TX
Click here to add this to my saved trials
JFK Medical Center
Atlantis, Florida 33462
?
mi
from
Atlantis, FL
Click here to add this to my saved trials
Doctors Hospital of Augusta
Augusta, Georgia 30909
?
mi
from
Augusta, GA
Click here to add this to my saved trials
Medical Center of Aurora
1501 S Potomac St
Aurora, Colorado 80012
(303) 695-2600
Medical Center of Aurora At The Medical Center of Aurora and Centennial Medical Plaza patients...
?
mi
from
Aurora, CO
Click here to add this to my saved trials
South Austin Hospital
Austin, Texas 78745
?
mi
from
Austin, TX
Click here to add this to my saved trials
North Austin Medical Center
Austin, Texas 78758
?
mi
from
Austin, TX
Click here to add this to my saved trials
Aventura Hospital
Aventura, Florida 33180
?
mi
from
Aventura, FL
Click here to add this to my saved trials
Belton Regional Medical Center
Belton, Missouri 64012
?
mi
from
Belton, MO
Click here to add this to my saved trials
LewisGale Hospital - Montgomery
Blacksburg, Virginia 24060
?
mi
from
Blacksburg, VA
Click here to add this to my saved trials
Lakeview Hospital
Bountiful, Utah 84010
?
mi
from
Bountiful, UT
Click here to add this to my saved trials
Greenview Regional Hospital
Bowling Green, Kentucky 42104
?
mi
from
Bowling Green, KY
Click here to add this to my saved trials
Blake Medical Center
Bradenton, Florida 34209
?
mi
from
Bradenton, FL
Click here to add this to my saved trials
Brandon Regional
Brandon, Florida 33511
?
mi
from
Brandon, FL
Click here to add this to my saved trials
Oak Hill Hospital
Brooksville, Florida 34613
?
mi
from
Brooksville, FL
Click here to add this to my saved trials
Valley Regional Medical Center
Brownsville, Texas 78526
?
mi
from
Brownsville, TX
Click here to add this to my saved trials
West Valley Medical Center
Caldwell, Idaho 83605
?
mi
from
Caldwell, ID
Click here to add this to my saved trials
Cartersville Medical Center
Cartersville, Georgia 30120
?
mi
from
Cartersville, GA
Click here to add this to my saved trials
Trident Regional Medical Center
Charleston, South Carolina 29406
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Parkridge Medical Center
Chattanooga, Tennessee 37404
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
Parkridge East Hospital
Chattanooga, Tennessee 37412
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
Conroe Regional Medical Center
Conroe, Texas 77304
?
mi
from
Conroe, TX
Click here to add this to my saved trials
Corpus Christi Medical Center - Doctor's
Corpus Christi, Texas 78411
?
mi
from
Corpus Christi, TX
Click here to add this to my saved trials
Corpus Christi Medical Center - The Heart Hospital
Corpus Christi, Texas 78412
?
mi
from
Corpus Christi, TX
Click here to add this to my saved trials
Lakeview Regional Medical Center
Covington, Louisiana 70433
?
mi
from
Covington, LA
Click here to add this to my saved trials
Denton Regional Medical Center
Denton, Texas 76210
?
mi
from
Denton, TX
Click here to add this to my saved trials
Swedish Medical Center
Denver, Colorado 80110
?
mi
from
Denver, CO
Click here to add this to my saved trials
Sky Ridge Medical Center
Denver, Colorado 80124
?
mi
from
Denver, CO
Click here to add this to my saved trials
Rose Medical Center
4567 E 9th Ave
Denver, Colorado 80220
(303) 320-2121
Rose Medical Center Well known as a Denver institution and a 9th Avenue landmark for...
?
mi
from
Denver, CO
Click here to add this to my saved trials
Parkland Medical Center
Derry, New Hampshire 03038
?
mi
from
Derry, NH
Click here to add this to my saved trials
Fairview Park
Dublin, Georgia 31021
?
mi
from
Dublin, GA
Click here to add this to my saved trials
Las Palmas Medical Center
El Paso, Texas 79902
?
mi
from
El Paso, TX
Click here to add this to my saved trials
Del Sol Medical Center
El Paso, Texas 79925
?
mi
from
El Paso, TX
Click here to add this to my saved trials
Englewood Community Hospital
Englewood, Florida 34223
?
mi
from
Englewood, FL
Click here to add this to my saved trials
Lawnwood Regional Medical Center
Fort Pierce, Florida 34950
?
mi
from
Fort Pierce, FL
Click here to add this to my saved trials
Fort Walton Medical Center
Fort Walton Beach, Florida 32547
?
mi
from
Fort Walton Beach, FL
Click here to add this to my saved trials
Plaza Medical Center of Fort Worth
Fort Worth, Texas 76104
?
mi
from
Fort Worth, TX
Click here to add this to my saved trials
Spotsylvania Regional Medical Center
Fredericksburg, Pennsylvania 22408
?
mi
from
Fredericksburg, PA
Click here to add this to my saved trials
North Florida Regional Medical Center
Gainesville, Florida 32605
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
Garden Park Medical Center
Gulfport, Mississippi 39503
?
mi
from
Gulfport, MS
Click here to add this to my saved trials
Hendersonville Medical Center
Hendersonville, Tennessee 37075
?
mi
from
Hendersonville, TN
Click here to add this to my saved trials
Summit Medical Center
Hermitage, Tennessee 37076
?
mi
from
Hermitage, TN
Click here to add this to my saved trials
John Randolph Medical Center
Hopewell, Virginia 23860
?
mi
from
Hopewell, VA
Click here to add this to my saved trials
East Houston Regional Medical Center
Houston, Texas 77015
?
mi
from
Houston, TX
Click here to add this to my saved trials
West Houston Medical Center
Houston, Texas 77082
?
mi
from
Houston, TX
Click here to add this to my saved trials
Regional Medical Center Bayonet Point
14000 Fivay Road
Hudson, Florida 34667
?
mi
from
Hudson, FL
Click here to add this to my saved trials
Eastern Idaho Regional
Idaho Falls, Idaho 83404
?
mi
from
Idaho Falls, ID
Click here to add this to my saved trials
Centerpoint Medical Center LLC
Independence, Missouri 64057
?
mi
from
Independence, MO
Click here to add this to my saved trials
Las Colinas Medical Center
Irving, Texas 75039
?
mi
from
Irving, TX
Click here to add this to my saved trials
Memorial Hospital Jacksonville
Jacksonville, Florida 32216
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Research Medical Center
2316 E Meyer Blvd
Kansas City, Missouri 64132
(816) 276-4000
Research Medical Center Research Medical Center offers hospital and health clinic services across three Kansas...
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Kingwood Medical Center
Kingwood, Texas
?
mi
from
Kingwood, TX
Click here to add this to my saved trials
Osceola Regional Med Ctr
Kissimmee, Florida 34741
?
mi
from
Kissimmee, FL
Click here to add this to my saved trials
Poinciana Medical Center
Kissimmee, Florida 34758
?
mi
from
Kissimmee, FL
Click here to add this to my saved trials
Lake City Medical Center
Lake City, Florida 32055
?
mi
from
Lake City, FL
Click here to add this to my saved trials
Largo Medical Center
Largo, Florida 33770
?
mi
from
Largo, FL
Click here to add this to my saved trials
Sunrise Hospital and Medical Center
Las Vegas, Nevada 89109
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Mountainview Hospital - Vegas
Las Vegas, Nevada 89128
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Southern Hills Hospital - Vegas
Las Vegas, Nevada 89148
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Lee's Summit Medical Center
Lee's Summit, Missouri 64063
?
mi
from
Lee's Summit, MO
Click here to add this to my saved trials
Medical Center of Lewisville
Lewisville, Texas 75057
?
mi
from
Lewisville, TX
Click here to add this to my saved trials
LewisGale Hospital-Alleghany
Low Moor, Virginia 24457
?
mi
from
Low Moor, VA
Click here to add this to my saved trials
Palms West Hospital
13001 Southern Boulevard
Loxahatchee Groves, Florida 33470
?
mi
from
Loxahatchee Groves, FL
Click here to add this to my saved trials
Coliseum Medical Centers - Main
Macon, Georgia 31217
?
mi
from
Macon, GA
Click here to add this to my saved trials
Coliseum Medical Centers - Northside
Macon, Georgia 31217
?
mi
from
Macon, GA
Click here to add this to my saved trials
Northwest Medical Center
Margate, Florida 33063
?
mi
from
Margate, FL
Click here to add this to my saved trials
Rio Grande Regional Hospital
McAllen, Texas 78503
?
mi
from
McAllen, TX
Click here to add this to my saved trials
Medical Center of McKinney
McKinney, Texas 75069
?
mi
from
McKinney, TX
Click here to add this to my saved trials
Mercy Hospital
Miami, Florida 33133
?
mi
from
Miami, FL
Click here to add this to my saved trials
Kendall Regional Medical Center
Miami, Florida 33175
?
mi
from
Miami, FL
Click here to add this to my saved trials
Grand Strand Regional Medical Center
Myrtle Beach, South Carolina 29572
?
mi
from
Myrtle Beach, SC
Click here to add this to my saved trials
Stonecrest Medical Center
Nashville, Tennessee 37167
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Centennial Medical Center
Nashville, Tennessee 37203
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Skyline Medical Center
Nashville, Tennessee 37207
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Southern Hills Medical Center
Nashville, Tennessee 37211
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Tulane University Hospital & Clinic
New Orleans, Louisiana 70112
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
Twin Cities Hospital
Niceville, Florida 32578
?
mi
from
Niceville, FL
Click here to add this to my saved trials
North Hills Hospital
North Richland Hills, Texas 76180
?
mi
from
North Richland Hills, TX
Click here to add this to my saved trials
Ocala Regional Medical Center
Ocala, Florida 34480
?
mi
from
Ocala, FL
Click here to add this to my saved trials
West Marion Community Hospital
Ocala, Florida 34474
?
mi
from
Ocala, FL
Click here to add this to my saved trials
Ogden Regional Medical Center
5475 South 500 East
Ogden, Utah 84405
?
mi
from
Ogden, UT
Click here to add this to my saved trials
Raulerson Hospital
Okeechobee, Florida 34972
?
mi
from
Okeechobee, FL
Click here to add this to my saved trials
Orange Park Medical Center
Orange Park, Florida 32073
?
mi
from
Orange Park, FL
Click here to add this to my saved trials
Timpanogos Regional Medical Center
750 West 800 North
Orem, Utah 84057
?
mi
from
Orem, UT
Click here to add this to my saved trials
Menorah Medical Center
5721 W 119th St
Overland Park, Kansas 66209
(913) 498-6000
Menorah Medical Center Menorah Medical Center (MMC), a full-service, acute care hospital located on the...
?
mi
from
Overland Park, KS
Click here to add this to my saved trials
Overland Park Regional Medical Center
Overland Park, Kansas 66215
?
mi
from
Overland Park, KS
Click here to add this to my saved trials
Gulf Coast Medical Center
Panama City, Florida 32405
?
mi
from
Panama City, FL
Click here to add this to my saved trials
Bayshore Medical Center
Pasadena, Texas 77504
?
mi
from
Pasadena, TX
Click here to add this to my saved trials
Mountain View Hospital - Utah
Payson, Utah 84651
?
mi
from
Payson, UT
Click here to add this to my saved trials
West Florida Hospital
Pensacola, Florida 32514
?
mi
from
Pensacola, FL
Click here to add this to my saved trials
The Medical Center of Plano
Plano, Texas 75075
?
mi
from
Plano, TX
Click here to add this to my saved trials
Plantation General Hospital
Plantation, Florida 33317
?
mi
from
Plantation, FL
Click here to add this to my saved trials
Westside Regional Medical Center
Plantation, Florida 33324
?
mi
from
Plantation, FL
Click here to add this to my saved trials
Fawcett Memorial Hospital
Port Charlotte, Florida 33952
?
mi
from
Port Charlotte, FL
Click here to add this to my saved trials
St Lucie Medical Center
Port Saint Lucie, Florida 34952
?
mi
from
Port Saint Lucie, FL
Click here to add this to my saved trials
Portsmouth Regional Hospital
Portsmouth, New Hampshire 03801
?
mi
from
Portsmouth, NH
Click here to add this to my saved trials
LewisGale Hospital - Pulaski
Pulaski, Virginia 24301
?
mi
from
Pulaski, VA
Click here to add this to my saved trials
Reston Hospital
Reston, Virginia 20190
?
mi
from
Reston, VA
Click here to add this to my saved trials