A Study of Galcanezumab (LY2951742) in Adults With Treatment-Resistant Migraine



Status:Active, not recruiting
Conditions:Migraine Headaches
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 75
Updated:4/5/2019
Start Date:July 31, 2018
End Date:October 6, 2019

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A Randomized, Double-Blind, Placebo-Controlled Study of Galcanezumab in Adults With Treatment-Resistant Migraine - the CONQUER Study

The purpose of this study is to assess the safety and efficacy of galcanezumab in people with
treatment-resistant episodic or chronic migraine.


Inclusion Criteria:

- Have a diagnosis of migraine or chronic migraine.

- History of migraine headaches at least 1 year prior to screening, with onset prior to
age 50.

- Have failed previous migraine preventive medications in the past 10 years due to
inadequate efficacy or tolerability.

Exclusion Criteria:

- Are currently enrolled in or have participated within the last 30 days or within 5
half-lives (whichever is longer) in a clinical trial involving an investigational
product.

- Current use or prior exposure to galcanezumab or another calcitonin gene-related
peptide (CGRP) antibody.

- History of persistent daily headache, cluster headache or migraine subtypes including
hemiplegic (sporadic or familial) migraine, ophthalmoplegic migraine, and migraine
with brainstem aura (basilar-type migraine).

- Pregnant or nursing.
We found this trial at
19
sites
4202 E Fowler Ave
Tampa, Florida 33620
(813) 974-2011
Principal Investigator: Kavita Kalidas
Phone: 321-331-6768
University of South Florida The University of South Florida is a high-impact, global research university...
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Albuquerque, New Mexico
Principal Investigator: Marigene D Salazar Sharma
Phone: 505-224-7407
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Allentown, Pennsylvania 18104
Principal Investigator: Paul K. Gross
Phone: 610-820-0342
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Ann Arbor, Michigan 48104
Principal Investigator: Joel R. Saper
Phone: 734-677-6000
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Bellevue, Washington 98007
Principal Investigator: Arifulla Khan
Phone: 425-453-0404
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Boston, Massachusetts 02135
Principal Investigator: Arkadiy Stolyar
Phone: 617-477-4868
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Brugge,
Principal Investigator: Annelies Van Dycke
Phone: 3250452370
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Greensboro, North Carolina 27408
Principal Investigator: Randal L. Von Seggern
Phone: 336-574-8020
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Minneapolis, Minnesota 55402
Principal Investigator: Gary D. Berman
Phone: 612-333-2200
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Mount Pleasant, South Carolina 29464
Principal Investigator: Cynthia B Strout
Phone: 843-856-3784
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Nashua, New Hampshire 03060
Principal Investigator: Hisham M. Hafez
Phone: 603-880-9880
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Newport News, Virginia 23606
Principal Investigator: Chester Fisher, Jr.
Phone: 757-591-8100
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Ocoee, Florida 34761
Principal Investigator: Kelly Taylor
Phone: 407-654-2724
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Phoenix, Arizona 85004
Principal Investigator: Joshua Tobin
Phone: 602-265-6500
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Rochester, New York 14609
Principal Investigator: Matthew G Davis
Phone: 585-288-0890
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Salt Lake City, Utah 84109
Principal Investigator: Dan C Henry
Phone: 801-486-3021
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San Diego, California 92108
Principal Investigator: Dane M. Shipp
Phone: 619-521-2830
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Toms River, New Jersey 08755
Principal Investigator: Ashok Patel
Phone: 732-244-2299
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Wesley Chapel, Florida 33544
Principal Investigator: Katherine Standley
Phone: 352-629-5800
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