A Sleep Intervention (SLEEP-Extend) for Young Adults At-Risk for Type 2 Diabetes

Insulin Resistance has been shown to put a person at risk for developing Type II diabetes.
There is a correlation between sleep deprivation and insulin resistance.The study wants to
assess the feasibility by enrolling 20 subjects in a year. The study also wants to assess the
feasibility of the sleep extension intervention among young adults by examining the number of
subjects that are randomized to intervention arm will complete the study.

Another intent of the study is to examine how sleep behaviors affect risks for developing
type 2 diabetes and to determine their willingness to participate in a 4-week home-based
program (intervention) focused on personal sleep behaviors.

Subjects enrolled in the study and are randomized to intervention group and control group.
The intervention group will receive one education session consisting of strategies for sleep
hygiene which is the routine for going to sleep and instructions on extending time in bed by
at least one hour but can be up to 2 hours total per night for 4 weeks. At the end of 4 weeks
subjects will have a blood draw and will complete the questionnaires.

Inclusion Criteria:

- Age must be 18-25 years old

- Subject has the ability to read and write English

- Baseline HOMA-IR of ≥ 2.1

- Short sleep duration of < 6 hours/night (as measured by actigraphy for 7 days)

- BMI (kg/m2) of 25 or more

- Asking if they are willing to participate in a 4-week program focusing on sleep
behavior

- Administration of the Insomnia Severity Index (valid and reliable) to determine sleep
quality (Inclusion criteria includes good quality sleep and is total score of < 15)

Exclusion Criteria:

- Oxygen desaturation index ≥ 5/hour (as measured by 2 nights of pulse oximetry)

- Night shift worker;

- Sleep disorder diagnosis;

- Medical diagnosis of diabetes or pre-diabetes;

- Currently pregnant or lactating or with history of gestational diabetes;

- Actively participating in a weight loss program;

- Hospitalization in past 3 months for any medical or psychiatric condition;

- Having a major chronic illness (e.g. cancer, Lupus)]