Corticosteroid Sparing Effect of Certolizumab in Crohn's Disease

Inclusion Criteria:

- Men and women

- Age 18 years or older with moderate to severe Crohn's disease (Crohn's Disease
Activity Index (CDAI) score of ≥ 220 ≤450)

Exclusion Criteria:

- Active or draining fistula present at screening

- Lactating and/or pregnant female subjects

- A history of any health condition that could potentially interfere with the disease
and/or the treatment

- A history of an adverse reaction to polyethylene glycol (PEG) or a protein medicinal
product

- Any other condition which in the Investigator's judgment would make the patient
unsuitable for inclusion in the study

- History of drug or alcohol abuse in the prior year

- Receipt of any experimental therapy within or outside a clinical trial in the 3 months
prior to Visit 0