Pain and Sensation After Regional Anesthesia - Pilot Study
| Status: | Recruiting |
|---|---|
| Conditions: | Arthritis, Osteoarthritis (OA) |
| Therapuetic Areas: | Rheumatology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 9/2/2018 |
| Start Date: | August 16, 2018 |
| End Date: | October 2018 |
| Contact: | Christopher J Edwards, MD |
| Email: | chedward@wakehealth.edu |
| Phone: | +13367168222 |
Pilot Study on Pain and Sensation After Regional Anesthesia for Total Hip Arthroplasty
This study aims to determine spinal resolution and pain levels after the placement of a
lumbar plexus block (LPB) and spinal for total hip replacement procedure. This is a pilot
study that looks to collect information in order to design a larger, more significant study
comparing Quadratus Lumborum blocks (QLB) and Lumbar Plexus blocks.
lumbar plexus block (LPB) and spinal for total hip replacement procedure. This is a pilot
study that looks to collect information in order to design a larger, more significant study
comparing Quadratus Lumborum blocks (QLB) and Lumbar Plexus blocks.
The Quadratus Lumborum block (QLB) is a newer regional analgesic technique that may be as
effective as Lumbar Plexus blocks (LPB) at providing pain control following direct anterior
approach (DAA) hip arthroplasty. The purpose of this study is to collect pilot data to help
the design of a future randomized study, comparing a QLB to a LPB for DAA procedures. The
investigators will assess for spinal resolution below the level of L5/S1 by assessing the
presence of pin prick sensation at these levels. This will help determine if pain scores
collected at 6hrs reflect analgesia provided by the preoperative LPB alone or if the data is
confounded by the presence of spinal anesthesia. This data will help us determine if 6hrs is
a feasible primary endpoint to assess pain scores. Additionally, assuming that spinal
regression is complete by 6hrs, the VAS pain scores obtained will then be used to perform a
power analysis to determine the necessary study size when comparing QLB to LPB for DAA hip
arthroplasty.
effective as Lumbar Plexus blocks (LPB) at providing pain control following direct anterior
approach (DAA) hip arthroplasty. The purpose of this study is to collect pilot data to help
the design of a future randomized study, comparing a QLB to a LPB for DAA procedures. The
investigators will assess for spinal resolution below the level of L5/S1 by assessing the
presence of pin prick sensation at these levels. This will help determine if pain scores
collected at 6hrs reflect analgesia provided by the preoperative LPB alone or if the data is
confounded by the presence of spinal anesthesia. This data will help us determine if 6hrs is
a feasible primary endpoint to assess pain scores. Additionally, assuming that spinal
regression is complete by 6hrs, the VAS pain scores obtained will then be used to perform a
power analysis to determine the necessary study size when comparing QLB to LPB for DAA hip
arthroplasty.
Inclusion Criteria:
- Patients that have elective total hip arthroplasty with DAA at Davie Medical Center.
Exclusion Criteria:
- Patients will be excluded if they do not receive a lumbar plexus block and spinal
anesthesia.
- and/or if they have peripheral neuropathy affecting their feet.
We found this trial at
1
site
Bermuda Run, North Carolina 27006
Principal Investigator: Christopher J Edwards, MD
Phone: 336-716-8222
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