Power Training Combined With Interval Treadmill Training
| Status: | Recruiting |
|---|---|
| Conditions: | Neurology, Neurology, Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 10 - 17 |
| Updated: | 8/12/2018 |
| Start Date: | October 1, 2018 |
| End Date: | June 30, 2023 |
| Contact: | Noelle G Moreau, PhD |
| Email: | nmorea@lsuhsc.edu |
| Phone: | 504-568-4291 |
Power Training Combined With Interval Treadmill Training to Improve Walking Activity in Cerebral Palsy (PT³)
Ambulatory children with cerebral palsy (CP) experience walking limitations which negatively
influence their ability to physically participate in day to day life. The investigators
propose that impaired muscle power generation is the key limiting factor affecting walking
activity and participation. This proposal represents a combined approach where participants
undergo resistance training for muscle power generation in combination with locomotor
treadmill training that is based on typical pediatric walking and activity patterns rather
than adult protocols, which are endurance or time-based. Therefore, the primary objective of
this randomized controlled trial is to determine the effect of lower extremity Power Training
combined with interval Treadmill Training (PT³) on functional walking capacity and
community-based activity and participation in children with CP. We hypothesize that
remediating the most pronounced muscle performance impairment (i.e., muscle power) with power
training combined with a task- specific approach to walking that is developmentally
appropriate will have a significant effect on walking capacity and performance.
influence their ability to physically participate in day to day life. The investigators
propose that impaired muscle power generation is the key limiting factor affecting walking
activity and participation. This proposal represents a combined approach where participants
undergo resistance training for muscle power generation in combination with locomotor
treadmill training that is based on typical pediatric walking and activity patterns rather
than adult protocols, which are endurance or time-based. Therefore, the primary objective of
this randomized controlled trial is to determine the effect of lower extremity Power Training
combined with interval Treadmill Training (PT³) on functional walking capacity and
community-based activity and participation in children with CP. We hypothesize that
remediating the most pronounced muscle performance impairment (i.e., muscle power) with power
training combined with a task- specific approach to walking that is developmentally
appropriate will have a significant effect on walking capacity and performance.
The primary purpose of this randomized controlled trial is to test the effect of Power
Training combined with interval Treadmill Training (PT³) on walking capacity and performance
in children with CP with walking limitations. To identify key muscular mechanisms associated
with improved walking mobility, the effects of PT³ on muscle performance and architecture
will be examined. The premise of the PT³ protocol is that a combined impairment and
task-specific approach that is developmentally appropriate and targets muscle power deficits
specifically, is necessary to drive changes in both clinic and community-based walking
activity.
In this randomized multi-site clinical trial, 48 ambulatory participants with CP will receive
either PT³ or an equivalent dosage of traditional strength training combined with traditional
treadmill training (comparison group) for 24 sessions, 3 times per week for 8 weeks. Outcomes
will be collected at baseline and immediately post-treatment. Short and long-term retention
effects will be assessed at 2 and 6 months post.
Training combined with interval Treadmill Training (PT³) on walking capacity and performance
in children with CP with walking limitations. To identify key muscular mechanisms associated
with improved walking mobility, the effects of PT³ on muscle performance and architecture
will be examined. The premise of the PT³ protocol is that a combined impairment and
task-specific approach that is developmentally appropriate and targets muscle power deficits
specifically, is necessary to drive changes in both clinic and community-based walking
activity.
In this randomized multi-site clinical trial, 48 ambulatory participants with CP will receive
either PT³ or an equivalent dosage of traditional strength training combined with traditional
treadmill training (comparison group) for 24 sessions, 3 times per week for 8 weeks. Outcomes
will be collected at baseline and immediately post-treatment. Short and long-term retention
effects will be assessed at 2 and 6 months post.
Inclusion Criteria:
- Diagnosis of bilateral spastic Cerebral Palsy (CP)
- Age 10 to 17 years inclusive
- GMFCS levels I, II, or III
Exclusion Criteria:
- Orthopedic or neurosurgery less than 12 months prior to enrollment
- Injection therapies (phenol, botulinum toxin) less than 3 months prior to enrollment
- Lacking greater than 25 degrees of knee extension
We found this trial at
2
sites
4800 Sand Point Way NE
Seattle, Washington 98105
Seattle, Washington 98105
(206) 987-2000
Phone: 206-884-2066
Seattle Children's Hospital Seattle Children’s Hospital specializes in meeting the unique physical, emotional and developmental...
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