Ultra Rapid Culture Independent Detection of High-Priority Carbapenem Resistant Enterobacteriaceae Directly From Blood
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Infectious Disease, Infectious Disease, Hematology |
| Therapuetic Areas: | Hematology, Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 7 - 89 |
| Updated: | 8/16/2018 |
| Start Date: | July 2015 |
| End Date: | January 2020 |
The purpose of this study is to develop a new and very rapid diagnostic test for identifying
a certain type of bacteria called Enterobacteriaceae in blood. Rapid identification of
bacteria will assist in decreasing the use of antibiotics and help more patients survive
bacterial infections of the blood.
a certain type of bacteria called Enterobacteriaceae in blood. Rapid identification of
bacteria will assist in decreasing the use of antibiotics and help more patients survive
bacterial infections of the blood.
It is our overall goal to develop a new diagnostic technology that will facilitate
antibacterial stewardship to reduce selective pressure and improve patient outcomes. The
Institute of Medicine has identified antibiotic resistance as one of the key microbial
threats to health in the United States and has prioritized decreasing inappropriate use of
antimicrobials as the primary solution to address this threat. The emergence of carbapenem
resistance among Enterobacteriaceae (CRE) in the United States represents a recent and severe
byproduct of excessive antimicrobial use with a high mortality rate in bacteremia. A major
barrier toward decreasing use of antimicrobials is lack of sensitive and accurate rapid
diagnostic tests for identifying bacterial etiologies of infection.
antibacterial stewardship to reduce selective pressure and improve patient outcomes. The
Institute of Medicine has identified antibiotic resistance as one of the key microbial
threats to health in the United States and has prioritized decreasing inappropriate use of
antimicrobials as the primary solution to address this threat. The emergence of carbapenem
resistance among Enterobacteriaceae (CRE) in the United States represents a recent and severe
byproduct of excessive antimicrobial use with a high mortality rate in bacteremia. A major
barrier toward decreasing use of antimicrobials is lack of sensitive and accurate rapid
diagnostic tests for identifying bacterial etiologies of infection.
Inclusion Criteria:
- Laboratory confirmed gram negative bacilli blood culture
Exclusion Criteria:
- Pregnancy
- Prisoner
We found this trial at
2
sites
University of Colorado Hospital, Site Top medical professionals, superior medicine and progressive change make University...
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Denver Health Medical Center Denver Health is a comprehensive, integrated organization providing level one care...
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