Abdominal Functional Electrical Stimulation to Reduce Hyperinflation in Chronic Obstructive Pulmonary Disease Patients
| Status: | Completed |
|---|---|
| Conditions: | Chronic Obstructive Pulmonary Disease, Pulmonary |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 40 - Any |
| Updated: | 8/17/2018 |
| Start Date: | March 2013 |
| End Date: | January 2014 |
Abdominal Functional Electrical Stimulation to Reduce Hyperinflation in Patients With Chronic Obstructive Pulmonary Disease: A Feasibility Study
This is an early feasibility study to investigate whether transcutaneous electrical
stimulation applied to the abdominal wall muscles synchronous with voluntary exhalation can
be used to support ventilation and affect hyperinflation in patients with chronic obstructive
pulmonary disease. As part of this study, the effect of a range of stimulation intensities
and stimulation timing profiles will be explored.
stimulation applied to the abdominal wall muscles synchronous with voluntary exhalation can
be used to support ventilation and affect hyperinflation in patients with chronic obstructive
pulmonary disease. As part of this study, the effect of a range of stimulation intensities
and stimulation timing profiles will be explored.
Inclusion Criteria:
- Post-bronchodilator FEV1/FVC ratio of less than 0.7 and post-bronchodilator FEV1
between 30 and 80 % predicted.
- Current or former smokers with at least a 20 pack year smoking history
- Over the age of forty
Exclusion Criteria:
- Female subjects who are pregnant
- Subjects unable to give informed consent
- Subjects unable to perform required activities of the study (e.g. Six minute walk
test)
- Subjects with an implanted electronic device (e.g. a cardiac pacemaker)
- Subjects who have had a chronic obstructive pulmonary disease exacerbation within 30
days prior to enrollment
- Considerable arthritic changes that limit exertion
- Patients on oral prednisone
- Patients with a hernia
- Patients with a history of pneumothorax within the last 5 years
- History of epilepsy
- History of Abnormal electrocardiogram suggestive of cardiac disease
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