Pharmacokinetics of Antiepileptics in Patients on CRRT



Status:Recruiting
Conditions:Renal Impairment / Chronic Kidney Disease
Therapuetic Areas:Nephrology / Urology
Healthy:No
Age Range:18 - 80
Updated:8/22/2018
Start Date:November 20, 2017
End Date:June 2019
Contact:Shamir N Kalaria, Pharm.D.
Email:skalaria@umaryland.edu
Phone:4107061480

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

Pharmacokinetics of Antiepileptic Drugs in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy

The purpose of the study is to measure levels of any of the following AEDs (levetiracetam,
phenobarbital, phenytoin, ketamine, valproic acid, lacosamide) in blood and effluent on
critically ill patients receiving CRRT in order to characterize drug pharmacokinetics and
optimize dosing strategies in patients on CRRT.


Inclusion Criteria:

- Expected to be on CRRT and receive any of the following for more than 24 hrs

- Expected to survive for more than 24 hrs

- Achievement of steady state drug concentrations prior to study enrollment

Exclusion Criteria:

- Pregnancy

- Age < 18

- Prisoner
We found this trial at
1
site
University of Maryland Medical Center
22 S Greene St
Baltimore, Maryland 21201
(410) 328-8667
Phone: 410-628-5644
University of Maryland Medical Center Founded in 1823 as the Baltimore Infirmary, the University of...
?
mi
from
Baltimore, MD
Click here to add this to my saved trials