Intraop Ventilation Management and Postop Pulmonary Complications in High Risk Patients for OSA



Status:Recruiting
Healthy:No
Age Range:18 - Any
Updated:8/23/2018
Start Date:March 18, 2017
End Date:December 2018
Contact:Samuel Lindsey, MD
Email:samuel.lindsey@osumc.edu
Phone:614-293-8487

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Intraoperative Ventilation Management and Postoperative Pulmonary Complications in Patients at High Risk for Obstructive Sleep Apnea

Lung protective ventilation (LPV) has been proposed to reduce the incidence of postoperative
pulmonary complications (PPCs), and protect against ventilator induced lung injury (VILI).

LPV was first introduced in the intensive care units but has been recently adopted in the
operating rooms. Obstructive sleep apnea (OSA) is a widely prevalent condition in obese
patients and requires special attention in the operating room. Screening for OSA risk in
surgical patients is a common practice. The STOP-BANG questionnaire is a common screening
tool for OSA (Snoring, Tiredness, Observed apnea, high blood Pressure, BMI, Age, Neck
circumference, and male Gender). The American Society of Anesthesiologists practice
guidelines for the perioperative management of patients with OSA do not recommend any
specific ventilation strategy to prevent PPCs in this population. To the knowledge of the
investigators, the association between intraoperative ventilation strategies and PPCs in
laparoscopic bariatric surgery patients, who have a high STOP-BANG score, has not been
adequately investigated. The investigators propose a retrospective chart review of patients,
18 years of age and older, who underwent laparoscopic bariatric surgery, in reverse
Trendelenburg position, using pressure controlled ventilation (PCV/PCV-VG) at the Ohio State
University Wexner Medical Center, between January 01, 2012 and November 22, 2016, to
determine whether intraoperative driving pressure is a predictor of postoperative pulmonary
complications. No procedures will be done for the sake of conducting this study except for a
retrospective review of patient charts. Preoperative and intraoperative variables will be
collected to determine their predictive value of postoperative complications. No risks to the
patients' health or well being are anticipated due to the conduct of the proposed study. No
immediate benefits to the patients from whom data was collected is anticipated either.
Results obtained from this study may provide valuable information on the preferred
ventilation strategies in the operating room for future patients who have a high risk of
postoperative lung complications.

Inclusion Criteria:

- Male or Female

- Age ≥ 18 y/o

- Patients who underwent laparoscopic bariatric surgery

- Surgery under general anesthesia with endotracheal intubation and pressure controlled
mode of ventilation (PCV or PCV-VG)

Exclusion Criteria:

- Pregnant females, prisoners

- Short procedures: time of mechanical ventilation < 60 minutes

- Patients who received volume controlled ventilation (VCV) mode

- Patients with past medical history of neuromuscular illnesses, pulmonary hypertension
or CHF
We found this trial at
1
site
410 W 10th Ave
Columbus, Ohio 43210
(614) 293-8652
Phone: 614-293-0775
The Ohio State University, Wexner Medical Center Located in Columbus, The Ohio State University Wexner...
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from
Columbus, OH
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