Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants

Status:	Recruiting
Conditions:	Peripheral Vascular Disease, Neurology
Therapuetic Areas:	Cardiology / Vascular Diseases, Neurology
Healthy:	No
Age Range:	Any
Updated:	9/29/2018
Start Date:	August 28, 2018
End Date:	August 2020
Contact:	Neeru Sarin, MBBS
Email:	neeru.sarin@duke.edu
Phone:	919-668-5341

The purpose of this study is to develop a novel noninvasive bedside optical coherence
tomography (OCT) imaging technique in newborn infants with HIE that improves our ability to
assess the range of retinal effects from HIE and to diagnose and monitor treatments of HIE.

Inclusion Criteria:

Infants are eligible if:

- Admitted to the intensive care nursery, outborn or inborn, with a clinical diagnosis
of HIE; and with the approval of the neonatologist

- A parent or legal guardian provides written informed consent

Exclusion Criteria:

Potentially eligible infants will be excluded if:

• Congenital or chromosomal anomaly that has a profound impact on brain or eye development
(e.g. anencephaly, congenital cataract or Peter's anomaly) and infants for whom there has
been a clinical decision to limit life support.

We found this trial at

sites

Duke University Health System

Durham, North Carolina

Principal Investigator: Cynthia A Toth, MD

Phone: 919-668-5341

from

Durham, NC