Magnesium and Vitamin D Supplementation and Cardiometabolic Outcomes
| Status: | Recruiting |
|---|---|
| Conditions: | Obesity Weight Loss, Obesity Weight Loss, Other Indications, Peripheral Vascular Disease, Gastrointestinal |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Endocrinology, Gastroenterology, Other |
| Healthy: | No |
| Age Range: | 30 - 70 |
| Updated: | 8/24/2018 |
| Start Date: | February 1, 2016 |
| End Date: | June 1, 2020 |
| Contact: | Deeptha Sukumar, PhD |
| Email: | deeptha.sukumar@drexel.edu |
| Phone: | 267-359-5854 |
Parathyroid Hormone and Cardiometabolic Outcomes in Obesity: Role of Magnesium and Vitamin D Supplementation
The purpose of this study is to investigate the effects of a combined vitamin D and magnesium
supplementation on parathyroid hormone and cardiometabolic health in persons living with
obesity.
supplementation on parathyroid hormone and cardiometabolic health in persons living with
obesity.
Individuals living with obesity are at a higher risk of cardiometabolic abnormalities and
high circulating parathyroid hormone. There is evidence suggesting that vitamin D may play a
role in cardiovascular health outcomes; however, the research is currently inconclusive.
Magnesium is a cofactor of vitamin D metabolism, and the prevalence of concurrent vitamin D
and magnesium deficiency is high. This study aims to investigate the effect of vitamin D and
magnesium supplements in individuals who are overweight and obese on parathyroid hormone and
cardiometabolic health.
high circulating parathyroid hormone. There is evidence suggesting that vitamin D may play a
role in cardiovascular health outcomes; however, the research is currently inconclusive.
Magnesium is a cofactor of vitamin D metabolism, and the prevalence of concurrent vitamin D
and magnesium deficiency is high. This study aims to investigate the effect of vitamin D and
magnesium supplements in individuals who are overweight and obese on parathyroid hormone and
cardiometabolic health.
Inclusion Criteria:
- BMI range 25-40 kg/m2
- 30-70 years of age
Exclusion Criteria:
- Presence of any acute illness in the past month
- Pre-existing chronic medical conditions or medications know to influence energy,
vitamin D, magnesium and calcium metabolism, levels of blood glucose, lipids and blood
pressure
- Individuals taking vitamin D and magnesium supplement greater than the Recommended
Daily allowance
- Participants taking any medications or have disease known to influence calcium or bone
metabolism
We found this trial at
1
site
1601 Cherry Street
Philadelphia, Pennsylvania 19102
Philadelphia, Pennsylvania 19102
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