Exercise Dosing for Pain in Healthy Participants



Status:Completed
Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:18 - 40
Updated:8/24/2018
Start Date:February 11, 2015
End Date:June 6, 2017

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Managing Pain: Testing the Dosing and Social Aspects of Exercise Therapy Using a Multi-school Collaborative Approach With Human Participants

In this study investigators will examine the effect of dose related to exercise therapy for
pain in healthy adult humans. An acute pain model will be employed to study the effect of
exercise dose on pain. Acute pain models are currently used to study pain (both acute and
chronic) in human samples as there is currently no chronic pain model.

This study is designed as a randomized controlled trial with repeated measures. The effect of
exercise dose on pain: subjects will be randomly assigned to one of four exercise groups: 1.)
no exercise (control); 2.) low dose exercise (3x/week); 3.) moderate dose exercise (5x/week).
4.) high dose exercise (10x/week).

Inclusion Criteria:

1. Between age 18-40

2. Normal BMI (18.5-25.0)

3. HR 60-100 bmp

4. BP less than or equal to 140/90

Exclusion Criteria:

1. Age <18 or >40 years

2. Cardiac, respiratory, neurological or musculoskeletal disease

3. Acute pain

4. Chronic pain condition

5. Diabetes

6. BMI ≥ 25.1 or ≤ 18.4

7. Regular participation in high intensity athletic/sporting activities

8. Sedentary

9. Anxiety or depression disorders

10. Tape allergy

11. Currently pregnant
We found this trial at
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Pittsburgh, Pennsylvania 15282
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Pittsburgh, PA
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