Mindfulness and Neural Cardiovascular Control in Humans
| Status: | Recruiting |
|---|---|
| Conditions: | High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 11/11/2018 |
| Start Date: | September 4, 2018 |
| End Date: | January 2021 |
| Contact: | Joanne Polzein |
| Email: | jpolzien@mtu.edu |
| Phone: | 906-487-2902 |
Randomized, Active-Control Study to Determine the Effect of Mindfulness-Based Stress Reduction on Sympathetic Activity and Arterial Stiffness
This study evaluates the impact of mindfulness-based stress reduction (MBSR) on sympathetic
nerve activity and arterial stiffness. The investigator's central hypothesis is that MBSR
will reduce sympathetic activity and arterial stiffness.
nerve activity and arterial stiffness. The investigator's central hypothesis is that MBSR
will reduce sympathetic activity and arterial stiffness.
This study will recruit male and female subjects with elevated blood pressure who will
participate in a randomized, active control study to examine the impact of mindfulness-based
stress reduction (MBSR) on blood pressure, muscle sympathetic nerve activity and arterial
stiffness. The study will utilize established techniques for assessing blood pressure
patterns (24-hour ambulatory monitoring), peripheral sympathetic activity (microneurography)
and vascular stiffness (applanation tonometry) in humans. This study includes a stress
management education class for the active control.
participate in a randomized, active control study to examine the impact of mindfulness-based
stress reduction (MBSR) on blood pressure, muscle sympathetic nerve activity and arterial
stiffness. The study will utilize established techniques for assessing blood pressure
patterns (24-hour ambulatory monitoring), peripheral sympathetic activity (microneurography)
and vascular stiffness (applanation tonometry) in humans. This study includes a stress
management education class for the active control.
Inclusion Criteria:
- Seated systolic blood pressure >119 mmHg and/or diastolic blood pressure >79 mmHg
- Body mass index <30 kg/m2
Exclusion Criteria:
- Smokers
- Diabetes
- Pregnant women
- History of autonomic dysfunction
- Cardiovascular medication
We found this trial at
1
site
1400 Townsend Drive
Houghton, Michigan 49931
Houghton, Michigan 49931
Principal Investigator: John J Durocher, PhD
Phone: 906-487-2902
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