PET/CT Study in the Diagnosis of Coronary Plaque



Status:Terminated
Conditions:Peripheral Vascular Disease, Cardiology, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:8/31/2018
Start Date:October 2007
End Date:September 2009

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Comparison of Cardiac Positron Emission Tomography/Computed Tomography (PET/CT) With Coronary Angiography (CA) and Intravascular Ultrasound (IVUS) in the Diagnosis and Characterization of Coronary Artery Plaque

This study is being done to determine if a picture taking test of the heart, positron
emission tomography/computed tomography (or cardiac PET/CT), can identify the blockages in
the heart arteries that lead to heart attacks when compared to the standard of heart
catheterization.

Heart catheterization, in which a thin plastic tube, or catheter, is placed into an artery in
the arm or leg and advanced into the heart arteries, is the procedure that you and your
doctor have decided to pursue to look for heart artery blockages. It is being performed as
part of your standard care and not for research purposes. The research procedure (cardiac
PET/CT), which will be performed at a later date is a combination of heart CT (a test that
involves the use of x-rays to identify heart artery blockages) and heart PET (an imaging test
that uses a radioactive drug to look at how the heart uses fuel (sugar and fats) These tests
will be combined (PET/CT) to look for the presence and type of blockage in your heart
arteries.

It is important to develop a test that can determine if and what type of blockage you have in
your heart arteries as the presence and type of heart artery blockage is a very important
predictor of heart attack and death from heart attack.

Inclusion Criteria:

- 18 years oof age or older

- referred for cardiac catheterization.

- coronary artery disease that does not need angioplasty.

Exclusion Criteria:

- history of cardiac stents

- bypass surgery

- bad kidney function

- unable to take beta blocker medication

- history of asthma

- allergies to egg containing products

- atrial fibrillation

- pregnancy

- breastfeeding

- overweight by definition of a BMI over 35.
We found this trial at
1
site
Saint Louis, Missouri 63110
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Saint Louis, MO
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