Silicone Gel for Postsurgical Scars of the Eyelid
Status: | Recruiting |
---|---|
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 9/15/2018 |
Start Date: | August 1, 2018 |
End Date: | August 1, 2020 |
Contact: | Jose Rosado |
Email: | jrosado@montefiore.org |
Phone: | 7189202020 |
Efficacy of Silicone Gel Versus Placebo for Postsurgical Scars of the Eyelid
To determine whether silicone gel is effective at preventing or minimizing scar formation
after eyelid surgery.
after eyelid surgery.
Upper eyelid blepharoplasty or ptosis repair is performed when the upper eyelid becomes
droopy, which often occurs as a natural part of the aging process. The droopiness of the
upper eyelids decreases the ability to see objects in their peripheral vision, causing
functional deficits. Additionally, the droopiness can be a cosmetic concern for many. The
most effective treatment option is blepharoplasty or ptosis repair.
During routine pre-operative counseling, many patients note a fear of prominent facial
scarring. Different techniques have been described in the literature to minimize scarring,
from steroid creams to injections to laser therapy; however, there is currently no consensus
for long-term management of post-surgical eyelid scars. Specifically, there is no study
examining the efficacy of topical silicone gel on eyelid scars, although a few studies have
examined its efficacy on other facial scars. Silicone is proposed to aid in healing by
regulating fibroblast production, reducing collagen production, and modifying expression of
growth factors.
The investigator's study is designed to determine whether topical silicone may prevent
significant post-operative eyelid scar formation. It may help clarify whether there is a safe
and effective topical treatment for patients undergoing eyelid surgery for whom scarring or
cosmesis is a concern. It is the first study of silicone gel on the eyelid and is also
prospective, randomized, and double blinded.
droopy, which often occurs as a natural part of the aging process. The droopiness of the
upper eyelids decreases the ability to see objects in their peripheral vision, causing
functional deficits. Additionally, the droopiness can be a cosmetic concern for many. The
most effective treatment option is blepharoplasty or ptosis repair.
During routine pre-operative counseling, many patients note a fear of prominent facial
scarring. Different techniques have been described in the literature to minimize scarring,
from steroid creams to injections to laser therapy; however, there is currently no consensus
for long-term management of post-surgical eyelid scars. Specifically, there is no study
examining the efficacy of topical silicone gel on eyelid scars, although a few studies have
examined its efficacy on other facial scars. Silicone is proposed to aid in healing by
regulating fibroblast production, reducing collagen production, and modifying expression of
growth factors.
The investigator's study is designed to determine whether topical silicone may prevent
significant post-operative eyelid scar formation. It may help clarify whether there is a safe
and effective topical treatment for patients undergoing eyelid surgery for whom scarring or
cosmesis is a concern. It is the first study of silicone gel on the eyelid and is also
prospective, randomized, and double blinded.
Inclusion Criteria:
- Patients will be included if they have met the criteria for undergoing upper eyelid
ptosis repair or blepharoplasty. This means they have droopiness of the upper eyelids
that is visually significant and limiting the patient's visual field.
Exclusion Criteria:
- Patients will be excluded if they require additional upper eyelid surgery.
We found this trial at
1
site
3550 Jerome Avenue
Bronx, New York 10467
Bronx, New York 10467
(718) 920-4321
Phone: 718-920-2020
Montefiore Medical Center As the academic medical center and University Hospital for Albert Einstein College...
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