Examining How Heart Disease Risk Factors Affect Healthy Aging (The Chicago Healthy Aging Study [CHAS])
| Status: | Completed |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 65 - 84 |
| Updated: | 2/8/2015 |
| Start Date: | November 2007 |
| End Date: | January 2011 |
Low CV Risk, Ages 25-44 & CV/Non-CV Outcomes, Ages 65+
Heart disease is the leading cause of death in the United States and is responsible for 30%
of all deaths in the United States. This study will examine how risk factors for heart
disease in young and middle aged people affect people's health as they grow older.
of all deaths in the United States. This study will examine how risk factors for heart
disease in young and middle aged people affect people's health as they grow older.
Heart disease, including coronary heart disease (CHD) and cardiovascular disease (CVD), is a
serious health problem in the United States. It is the leading cause of death in this
country, and each year almost 700,000 people die from the disease. Risk factors for heart
disease include high blood pressure, high cholesterol levels, tobacco use, diabetes, and
history of a prior heart attack. It has been shown that young and middle aged adults with
few risk factors experience a lower incidence of heart disease, lower Medicare costs, and
longer lives than those with more risk factors. However, it is not known how having a low
risk for heart disease at a young age affects health-related outcomes in older age. It may
be possible that a low risk for developing heart disease in younger years results in
healthier aging than does a higher risk. This study will examine former participants of the
Chicago Heart Association (CHA) study who are now 65 to 84 years old. The purpose of this
study is to determine how risk factors for heart disease in young adulthood and middle age
are related to healthy aging.
This study will enroll 1500 people who participated in the CHA study from 1967 to 1973 and
who are still living in the Greater Chicagoland area. Six hundred former participants who
had a low risk of developing heart disease and 900 former participants who had a high risk
of developing heart disease will be enrolled. Participants will attend one study visit that
will include medical history interviews and questionnaires, a physical examination, blood
pressure measurements, blood and urine collection, and an electrocardiogram (ECG) to measure
the electrical activity of the heart. Blood samples will be collected and stored for future
genetic testing. Participants will undergo physical functioning performance tests on
balance, leg strength and coordination, grip strength, and endurance. They will also undergo
a computed tomography chest scan to measure the amount of calcium in the arteries of the
heart and ultrasound scans of the arteries in the neck to measure artery size and function.
serious health problem in the United States. It is the leading cause of death in this
country, and each year almost 700,000 people die from the disease. Risk factors for heart
disease include high blood pressure, high cholesterol levels, tobacco use, diabetes, and
history of a prior heart attack. It has been shown that young and middle aged adults with
few risk factors experience a lower incidence of heart disease, lower Medicare costs, and
longer lives than those with more risk factors. However, it is not known how having a low
risk for heart disease at a young age affects health-related outcomes in older age. It may
be possible that a low risk for developing heart disease in younger years results in
healthier aging than does a higher risk. This study will examine former participants of the
Chicago Heart Association (CHA) study who are now 65 to 84 years old. The purpose of this
study is to determine how risk factors for heart disease in young adulthood and middle age
are related to healthy aging.
This study will enroll 1500 people who participated in the CHA study from 1967 to 1973 and
who are still living in the Greater Chicagoland area. Six hundred former participants who
had a low risk of developing heart disease and 900 former participants who had a high risk
of developing heart disease will be enrolled. Participants will attend one study visit that
will include medical history interviews and questionnaires, a physical examination, blood
pressure measurements, blood and urine collection, and an electrocardiogram (ECG) to measure
the electrical activity of the heart. Blood samples will be collected and stored for future
genetic testing. Participants will undergo physical functioning performance tests on
balance, leg strength and coordination, grip strength, and endurance. They will also undergo
a computed tomography chest scan to measure the amount of calcium in the arteries of the
heart and ultrasound scans of the arteries in the neck to measure artery size and function.
Inclusion Criteria:
- Participated in the CHA study
- Lives in the Greater Chicagoland area
Exclusion Criteria:
- Severely ill, disabled, or cognitively impaired
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