Genetic Basis of Rosacea Study (Control)
| Status: | Recruiting |
|---|---|
| Conditions: | Cosmetic |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 9/19/2018 |
| Start Date: | October 2015 |
| End Date: | November 2019 |
| Contact: | Anne L Chang, MD |
| Email: | alschang@stanford.edu |
| Phone: | 650 721 7151 |
Expansion Arm of Papulopustular Rosacea Gene Expression Profiling to Include Normal Individuals as Anatomic Site Specific Controls
Rosacea is a common disease characterized by inflammation and vascular abnormalities of the
facial skin and ocular surface. It it considered to be a syndrome encompassing various
combinations of cutaneous signs including flushing, erythema, telangiectasia, papules, edema,
ocular lesions, and rhinophyma. The exact etiology of cutaneous rosacea is unknown but is
characterized by persistent vasodilation, increased vascular permeability, and vascular
hyper-reactivity of the microcirculation of the central part of the face. The purpose of this
study is to develop gene expression profiles of papulopustular rosacea compared to those of
normal skin. The investigator hopes to better understand the abnormal gene functions that
might contribute to this condition. This understanding may lead to the development of
additional and better treatments for rosacea.
facial skin and ocular surface. It it considered to be a syndrome encompassing various
combinations of cutaneous signs including flushing, erythema, telangiectasia, papules, edema,
ocular lesions, and rhinophyma. The exact etiology of cutaneous rosacea is unknown but is
characterized by persistent vasodilation, increased vascular permeability, and vascular
hyper-reactivity of the microcirculation of the central part of the face. The purpose of this
study is to develop gene expression profiles of papulopustular rosacea compared to those of
normal skin. The investigator hopes to better understand the abnormal gene functions that
might contribute to this condition. This understanding may lead to the development of
additional and better treatments for rosacea.
Inclusion criteria include:
1. Fitzpatrick skin type II or III
2. Age greater than or equal to 18 years
3. Individuals without a history of rosacea
Exclusion criteria include:
1. Women who are pregnant or lactating
2. Use of topical prescription medications or procedures to the face within one month of
enrollment
3. Skin conditions that might interfere with interpretation of procedure results (at the
discretion of the investigator)
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