Safety of Pregnancy in BRCA Mutated Breast Cancer Patients
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Breast Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - 40 |
| Updated: | 9/19/2018 |
| Start Date: | January 16, 2017 |
| End Date: | June 2023 |
A Multicenter Retrospective Study on the Prognostic Impact of Pregnancy in Women With History of BRCA Mutated Breast Cancer
The present study aims at refining the understanding of the effect of pregnancy on breast
cancer outcomes in the specific population of BRCA mutated patients with known history of
breast cancer.
cancer outcomes in the specific population of BRCA mutated patients with known history of
breast cancer.
Inclusion Criteria:
- Diagnosis of invasive breast cancer between January 2000 and December 2012;
- Breast cancer diagnosis at the age of ≤ 40 years;
- Known presence of germline BRCA mutation.
Exclusion Criteria:
- Known BRCA mutation with no diagnosis of invasive breast cancer;
- Diagnosis of ovarian cancer or other malignancies with no history of invasive breast
cancer;
- Diagnosis of hereditary or familiar invasive breast cancer without BRCA mutation or
with BRCA genes not tested.
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Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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