Impact of Infant Formula on Caregiver-perceived Intolerance

Inclusion Criteria:

- Healthy infant

- Full-term (> 37 weeks gestation)

- Birth weight > 2500 and < 4500 g

- 14-60 days of age on enrollment

- Singleton birth

- Infant's mother has elected not to breastfeed prior to enrollment

- Infant exclusively formula-fed for at least 5 days prior to enrollment

- Caregiver perceives infant as very or extremely fussy according to perceived fussiness
based on the previous 3 days

- Caregiver wishes to switch infant's formula

- Has not received solid foods

- Having obtained his/her legal representative's informed consent

Exclusion Criteria:

- Known or suspected cow-milk allergy

- Currently receiving a specialty infant formula (e.g. thickened, extensively
hydrolyzed, amino acid-based, metabolic)

- Has switched formula more than two times since hospital discharge

- Currently experiencing gastrointestinal or respiratory symptoms secondary to an
ongoing infection or virus (e.g. gastrointestinal infection, upper respiratory
infection, flu)

- Congenital illness or malformation that may affect infant feeding and/or growth

- Any readmission to hospital (except for hyperbilirubinemia) prior to enrollment

- Receiving probiotic supplements

- Infant's family who in the Investigator's assessment cannot be expected to comply with
treatment (feeding regimen).

- Participation in another study that has not been approved as a concomitant study by
Nestlé Nutrition.