Weight Loss and Cognitive Function
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 50 - 75 |
| Updated: | 12/21/2018 |
| Start Date: | August 6, 2018 |
| End Date: | February 2019 |
Weight Loss and Cognitive Function in Middle-Aged and Older Adults
More than two-thirds of middle-aged and older adults are overweight, which places them at
greater risk of disability and higher medical expenses. Lifestyle interventions which promote
weight loss for this population are needed. However, it is not known how different weight
loss approaches impact brain (cognitive) functions, such as memory and attention. The
investigator's investigation aims to improve adherence to a hypocaloric diet prescription
through improved attention and inhibitory control, reduced hunger, and increased satiety.
The objectives of this pilot study are to: 1) determine the feasibility and establish
proof-of-concept; 2) establish proficiency and feasibility of the proposed cognitive function
assessments; and 3) obtain preliminary data for effect size generation.
greater risk of disability and higher medical expenses. Lifestyle interventions which promote
weight loss for this population are needed. However, it is not known how different weight
loss approaches impact brain (cognitive) functions, such as memory and attention. The
investigator's investigation aims to improve adherence to a hypocaloric diet prescription
through improved attention and inhibitory control, reduced hunger, and increased satiety.
The objectives of this pilot study are to: 1) determine the feasibility and establish
proof-of-concept; 2) establish proficiency and feasibility of the proposed cognitive function
assessments; and 3) obtain preliminary data for effect size generation.
Inclusion Criteria:
- Overweight or obese, BMI 25-40 kg/m^2
- Able to use a computer, keyboard, and mouse
Exclusion Criteria:
- Uncontrolled hypertension
- Orthopedic injury
- Other conditions that preclude participation in a walking program
- Previous participation in psychology research which involved computerized cognitive
testing
- Diabetes which requires insulin
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