Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization
| Status: | Recruiting |
|---|---|
| Conditions: | Infectious Disease, Hospital |
| Therapuetic Areas: | Immunology / Infectious Diseases, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 9/29/2018 |
| Start Date: | April 3, 2017 |
| End Date: | December 2023 |
| Contact: | Susan Huang, MD MPH |
| Email: | sshuang@uci.edu |
| Phone: | (949) 824-1455 |
This is a cluster-randomized trial of nursing homes to assess whether decolonization with
routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce
hospitalizations associated with infections, antibiotic utilization, and multi-drug resistant
organism (MDRO) prevalence. The comparator arm will be routine bathing care.
routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce
hospitalizations associated with infections, antibiotic utilization, and multi-drug resistant
organism (MDRO) prevalence. The comparator arm will be routine bathing care.
Inclusion Criteria
Nursing homes will be eligible to participate if they meet the following criteria:
- Licensed nursing home in Orange County or Southern Los Angeles County serving adults
- Minimal use of chlorhexidine bathing*
- Minimal use of nasal decolonization* *Minimal use defined as <15% of residents
receiving at least one chlorhexidine bath or nasal decolonization treatment during
their nursing home stay.
Exclusion Criteria
Nursing homes will not be eligible to participate if they meet the following criteria:
- Facilities routinely using decolonization
- Dedicated psychiatric nursing homes
- Facilities with a resident population with >=20% combative patients
- Pediatric facilities
Note: in any participating nursing home, residents with active end-of-life comfort care
only measures are excluded
We found this trial at
28
sites
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