Non Exudative AMD Imaged With SS-OCT

This is a longitudinal observational study where the investigators will look at 450 subjects,
200 with intermediate AMD in at least one eye, or with AMD in one eye, either early or
intermediate, and with late AMD (exudative) in the other eye, and 250 subjects with nGA or GA
in at least one eye.

Inclusion Criteria:

1. Aged 50 and over

2. Clinic diagnosis of non-exudative iAMD in at least one eye with a drusen volume in the
central 3 mm circle centered on the fovea of at least 0.02 mm3 in the absence of GA or
nGA as diagnosed with OCT en face imaging OR Clinical diagnosis of early or
early/intermediate stage AMD in one eye in the absence of nGA or GA and exudative AMD
in the other eye OR clinical diagnosis of GA or nGA secondary to AMD that is at least
the size of a large druse (125 microns in diameter; 0.05 mm2) and no greater than 7
disc areas (17 mm2) in at least one eye which has never been treated with anti-VEGF
agents

3. Willing and able to comply with clinic visits and study-related procedures

4. Provide signed informed consent

Exclusion Criteria:

A subject who meets any of the following criteria will be excluded from the study:

1. Below the age of 50

2. Subjects with exudative AMD in both eyes

3. Eyes with evidence of non-proliferative and proliferative diabetic retinopathy.

4. Presence of confounding ocular diagnosis such as myopia >6D, or other ocular
conditions that may cause retinal pigment epithelium atrophy or exudative MNV

5. Subjects unable to give informed consent.

6. Subjects who are unable to comply with imaging guidelines