A Study is to Understand the Treatment Patterns for Immunotherapy Agents and BRAF/MEK Inhibitors Used in the Treatment of Advanced Melanoma

Inclusion Criteria:

- Patients must have ≥1 medical or pharmacy claim for nivolumab, ipilimumab,
pembrolizumab, nivolumab+ipilimumab (on the same day), dabrafenib, vemurafenib,
cobimetinib, trametinib, dabrafenib+trametinib (on the same day) and
vemurafenib+cobimetinib (on the same day)

- Patients must have ≥6 months of continuous health plan enrollment prior to index date

- Patients must have ≥2 medical claims at least 30 days apart with a diagnosis for
melanoma during the study period AND ≥1 diagnosis for melanoma during the baseline
period prior to or on the index date

Exclusion Criteria:

- Patients with ≥1 claim for the agents of interest including immunotherapy agents and
BRAF/MEK inhibitors between the first diagnosis of metastatic disease and the day
prior to the index date will be excluded

- Patients with a claim for acquired immunodeficiency virus (AIDS) anytime during the
study period

- Patients under the age of 18 as of index date

Other protocol defined inclusion/exclusion criteria could apply