Bio-marker Analysis Using Circulating Tumor Cells in Patients With Melanoma



Status:Recruiting
Conditions:Skin Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:10/7/2018
Start Date:December 2013
Contact:Giorgos Karakousis, MD
Email:PennCancerTrials@emergingmed.com
Phone:855-216-0098

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This research trial studies the levels of a type of biomarker, circulating tumor cells
(CTCs), in the blood of patients with stage I-IV melanoma. A biomarker is a biological
molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal
process, or of a condition or disease. A biomarker may be used to see how well the body
responds to a treatment for a disease or condition. Studying samples of blood in the
laboratory obtained before and after treatment from patients with melanoma may help doctors
learn more about changes that occur in CTC levels and whether they may predict how well
patients will respond to therapy.


Inclusion Criteria:

- Subjects must have signed tissue collection consent as described in protocol IRB#
703001,UPCC# 08607, PI: Giorgos Karakousis, MD

- Subjects must be competent to consent for themselves.

- Subjectsmust be adult (18 years or older).

- Subjects must be initiating a new therapy for melanoma (so a pretreatment CTC count
can be obtained).

Exclusion Criteria:

- Children (less than 18yrs)

- Patients in whom a pre-treatment CTC level cannot be obtained.
We found this trial at
1
site
3400 Civic Center Blvd
Philadelphia, Pennsylvania 19104
(215) 662-6065
Principal Investigator: Giorgos Karakousis, MD
Phone: 855-216-0098
Abramson Cancer Center of the University of Pennsylvania The Abramson Cancer Center of the University...
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Philadelphia, PA
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