Opioid and Cannabinoid Interactions
| Status: | Not yet recruiting |
|---|---|
| Conditions: | Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 4/6/2019 |
| Start Date: | June 2019 |
| End Date: | December 2021 |
| Contact: | Shanna Babalonis, Ph.D. |
| Email: | babalonis@uky.edu |
| Phone: | (859) 257-1881 |
Interactions of Marijuana and Opioids: Pharmacodynamic Effects
This study will examine the effects of doses of marijuana/placebo and doses of
opioid/placebo, alone and in combination. The primary outcomes are related to pharmacodynamic
measures (subjective ratings of drug liking and other abuse-related effects; physiological
outcomes) to determine the interaction effects of these compounds.
opioid/placebo, alone and in combination. The primary outcomes are related to pharmacodynamic
measures (subjective ratings of drug liking and other abuse-related effects; physiological
outcomes) to determine the interaction effects of these compounds.
Inclusion Criteria:
- Healthy adults ages 18-50
- Current non-medical use of opioids and marijuana
Exclusion Criteria:
- Physical dependence on opioids, alcohol benzodiazepines/sedative/hypnotics
- Seeking treatment for drug use
- Significant medical problems
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