Effect of Location of Tetanic Stimuli on Photoplethysmogram



Status:Completed
Conditions:Orthopedic
Therapuetic Areas:Orthopedics / Podiatry
Healthy:No
Age Range:18 - Any
Updated:1/12/2019
Start Date:September 1, 2018
End Date:November 30, 2018

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Effect of Location of Tetanic Stimuli on Photopethysmogram During General Anesthesia

The effect of the location of tetanic stimulus on photoplethysmography signals will be
studies in patients under general anesthesia.

A 5 second 100 Hz 70 mA tetanic stimulus will be applied to three different locations in a
random order in patients who are under general anesthesia. Tetanic stimuli are used routinely
during general anesthesia to assess effectiveness of neuromuscular blockade. These tetanic
stimuli are noxious stimuli that elicit a stress response which can be quantified using
photoplethysmography. This study investigates if the magnitude of the tetanus induced stress
response is dependent on the location of the tetanic stimulus as measured by
photoplythysmography.

Inclusion Criteria:

- Surgical patients general anesthesia able to consent in english

Exclusion Criteria:

- regional anesthesia unable to consent in english under 18 yrs of age
We found this trial at
1
site
San Francisco, California 94143
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from
San Francisco, CA
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