Procalcitonin at Zero and 24 Hours as a Prognostic Factor in Patients With Pneumonia



Status:Recruiting
Conditions:Pneumonia
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:18 - Any
Updated:10/20/2018
Start Date:July 17, 2018
End Date:April 1, 2019
Contact:Tomasz Przednowek, DO
Email:tprzednowek1@lakelandhealth.org
Phone:269-983-8300

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Procalcitonin levels checked initially and at 24 hours will correlate with disease severity,
morbidity, and mortality. Patients who have a higher procalcitonin level initially and at 24
hours will likely have higher qSOFA scores, longer lengths of stay, longer duration of
antibiotics and higher 30 day mortality rates.

A procalcitonin order bundle will be created for admitted patients with pneumonia. This
prepopulated bundle includes an initial and 24 hour procalcitonin level, much like the
current initial and 4 hour lactate orders are set-up. These patients will receive treatment
for their pneumonia as is deemed appropriate by their care teams, both in the Emergency
Department and while an inpatient. Then, after discharge, the 30 day mortality, length of
stay, choice of antibiotic therapy, and qSOFA score (which will be retroactively calculated)
will be compared to the patient's initial and 24 hour procalcitonin level.

Inclusion Criteria:

- All patients seen at Lakeland St. Joseph and Niles Hospitals in the emergency
department and who are then subsequently admitted with pneumonia at Lakeland St.
Joseph and Niles Hospitals

Exclusion Criteria:

- Any patients not admitted with pneumonia, any patients who are admitted with another
primary diagnosis other than pneumonia, any patients who do not have an initial or 24
hour procalcitonin level result, and any patients less than 18 years old
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