Empiric Treatment for Acute HIV in the ED



Status:Not yet recruiting
Conditions:Infectious Disease, HIV / AIDS, HIV / AIDS
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:10/20/2018
Start Date:November 2018
End Date:November 2021
Contact:Esther Lim, MPH
Email:Esther.Lim@med.usc.edu
Phone:(323) 865-1645

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Trial Summary
Trial Overview
Inclusion Criteria

Empiric Treatment for Suspected Acute HIV Infection in the Emergency Department

An acceptance and feasibility study for immediate ART initiation and storage of laboratory
specimens for individuals with suspected acute HIV infection who are diagnosed in one of the
7 participating emergency rooms

Individuals with suspected acute HIV infection willing to start immediate ART treatment will
be given the ART regimen (bictegravir 50mg + tenofovir alafenamide 25 mg + emtricitabine 200
mg fixed dose combination) on the day of diagnosis. Those patients beginning immediate ART in
the ED who are willing to have additional laboratory specimens drawn in the ED and become
part of a cohort to receive ART and have ongoing biological specimens obtained and will be
followed for 48 weeks.

Inclusion Criteria:

- Suspected acute HIV infection

- agree to start immediate ART and to storage of laboratory specimens

Exclusion Criteria:

- Known chronic HIV infection

- severe renal or liver disease

- drug allergy/hypersensitivity

- prohibited medications

- pregnancy

- co-morbidity that the investigator feels would compromise safety, data interpretation,
or achieving study objectives
We found this trial at
2
sites
Rand Schrader Health and Research Clinic
Los Angeles, California 90033
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Los Angeles, CA
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LA County-USC Medical Center Emergency Department
Los Angeles, California 90033
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Los Angeles, CA
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