Study of the Safety and Effectiveness of JUVÉDERM VOLUX™ XC Injectable Gel for Restoring Jawline Definition

Inclusion Criteria:

- Has "Moderate" or "Severe" loss of jawline definition as determined by the EI using
the ALJDs (Grade 2 or 3 on the ALJDS) on both sides. The grade does not have to be the
same on both sides, but must be Grade 2 or 3

- Treating Investigator (TI) considers the subject's jaw amenable to an improvement of
at least 1 grade on the scale for the jawline definition

- Written Informed Consent (IC) has been obtained

Exclusion Criteria:

- Has ever received permanent facial implants (eg, polymethylmethacrylate, silicone,
polytetrafluoroethylene) anywhere in the face or neck, or is planning to be implanted
with any of these products during the study

- Has ever undergone fat injections in the malar, chin or jawline area or is planning to
undergo this procedure during the study

- Has undergone semipermanent dermal filler treatment (eg, calcium hydroxyapatite,
poly-L-lactic acid) below the subnasale within 36 months before enrollment or is
planning to undergo such treatment during the study

- Has received deoxycholic acid treatment in the submental region in the last 6 months

- Has active autoimmune disease

- Females who are pregnant, nursing, or planning a pregnancy during the course of the
study