Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid
| Status: | Recruiting |
|---|---|
| Conditions: | Urology |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 10/27/2018 |
| Start Date: | February 1, 2018 |
| End Date: | May 2019 |
| Contact: | Heather Crowe |
| Email: | Crowe.Heather1@mayo.edu |
| Phone: | 480-342-3987 |
Comparison of Urinary Tract Infections Rates Using 50% Dextrose Plus Washout Versus Normal Saline as Cystoscopy Fluid: a Prospective Study
Our study will compare the rates of postoperative urinary tract infections (UTI) between
patients who undergo cystoscopy using 50% dextrose injection plus bladder washout versus
normal saline after hysterectomy for benign indications. Primary outcome will be rates of
urinary tract infections at 6-9 days post-operatively. This will be defined as a urine
culture yielding greater than 100,000 gram-negative colony-forming units per milliliter.
patients who undergo cystoscopy using 50% dextrose injection plus bladder washout versus
normal saline after hysterectomy for benign indications. Primary outcome will be rates of
urinary tract infections at 6-9 days post-operatively. This will be defined as a urine
culture yielding greater than 100,000 gram-negative colony-forming units per milliliter.
This will be a prospective cohort study of the rate of UTIs after cystoscopic distention
media of normal saline with maximum injection of 40 cc of 50% dextrose plus 300 cc of normal
saline washout versus normal saline after hysterectomy for benign indications.
A pre-operative urine culture will be obtained via mid-stream clean catch prior to
administration of routine pre-operative prophylactic antibiotics.
At 6-9 days post-operatively, a repeat urine culture will be obtained via mid-stream clean
catch. Appropriate treatment will be administered if the urine culture is positive.Primary
outcome will be rates of urinary tract infections at 6-9 days post-operatively. This will be
defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units
per milliliter.
media of normal saline with maximum injection of 40 cc of 50% dextrose plus 300 cc of normal
saline washout versus normal saline after hysterectomy for benign indications.
A pre-operative urine culture will be obtained via mid-stream clean catch prior to
administration of routine pre-operative prophylactic antibiotics.
At 6-9 days post-operatively, a repeat urine culture will be obtained via mid-stream clean
catch. Appropriate treatment will be administered if the urine culture is positive.Primary
outcome will be rates of urinary tract infections at 6-9 days post-operatively. This will be
defined as a urine culture yielding greater than 100,000 gram-negative colony-forming units
per milliliter.
Inclusion Criteria:
- Preoperative scheduling CPT codes for hysterectomy
Exclusion Criteria:
- Discharged home with indwelling foley catheter
- Indwelling foley catheter > 24 hours
- Ureteral injury
- Chronic immunosuppression
- History of diabetes
- Recurrent UTIs (≥2 infections in six months or ≥3 infections in one year)
- Reported Chronic Kidney Disease
- Renal anomalies
We found this trial at
1
site
Scottsdale, Arizona 85259
Principal Investigator: Jeffrey Cornella, MD
Phone: 480-342-3987
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