MT10109L in the Treatment of Glabellar Lines With or Without Concurrent Treatment of Lateral Canthal Lines

Inclusion Criteria

• Female participants must not be pregnant or planning to get pregnant and willing to
minimize the risk of inducing pregnancy for the duration of the clinical study and
follow-up period.

Exclusion Criteria

- Known immunization or hypersensitivity to any botulinum toxin serotype.

- Any medical condition that may put the participant at increased risk with exposure to
MT10109L including diagnosed myasthenia gravis, Eaton-Lambert syndrome, amyotrophic
lateral sclerosis, or any other condition that might interfere with neuromuscular
function.

- History of facial nerve palsy.

- Any uncontrolled systemic disease.

- Anticipated need for treatment with botulinum toxin of any serotype for any reason
during the study (other than study intervention).

- Anticipated need for surgery or overnight hospitalization during the study.

- Prior exposure to botulinum toxin of any serotype for any reason.

- Prior periorbital surgery, facial lift (full face or mid-face), thread lift, brow
lift, or related procedures (eg, eyelid [blepharoplasty] and/or eyebrow surgery).

- Prior facial treatment with permanent soft tissue fillers, synthetic implantation (eg,
Gore-Tex®), and/or autologous fat transplantation.

- Current enrollment in an investigational drug or device study or participation in such
a study within 30 days of entry into this study.

- Females who are pregnant, nursing, or planning a pregnancy during the study.

- Participants who plan for an extended absence away from the immediate area of the
study site that would preclude them from returning for all protocol-specified study
visits.