Exercise and Motor Learning After Stroke



Status:Active, not recruiting
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 85
Updated:11/2/2018
Start Date:June 12, 2018
End Date:June 2024

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Trial Summary
Trial Overview
Inclusion Criteria

Feedback and Cognition During Locomotor Learning Post Stroke

Subjects with chronic stroke (> 6 months post-stroke) will learn a new walking pattern
through distorted visual feedback. Retention of the pattern will be tested without visual
feedback immediately after learning and 24 hours later. Subjects will be randomly assigned to
the control group or the exercise group. The control group will simply complete the learning
task. The exercise group will complete 5 minutes of exercise immediately following the first
retention test to test for the effects of exercise on retention 24 hours later.


Inclusion Criteria:

- Age 18-85

- Single, unilateral, chronic stroke (>6 months post-stroke), confirmed by MRI or CT
scan

- Score >1 on question 1b and >0 on question 1c of the NIH Stroke Scale

- Able to walk at self-selected speed without assistance from another person

- Resting heart rate between 40-100 beats per minute

- Resting blood pressure between 90/60 to 185/100

Exclusion Criteria:

- Evidence of cerebellar stroke on clinical MRI or CT scan, because of role of
cerebellum in learning

- Other neurologic conditions in addition to stroke

- Inability to walk outside the home prior to the stroke

- Coronary artery bypass graft or myocardial infarction within past 3 months,

- Musculoskeletal pain that limits walking

- Inability to communicate with investigators

- Visual field cut

- Neglect

- Unexplained dizziness in last 6 months
We found this trial at
1
site
University of Delaware
Newark, Delaware 19716
?
mi
from
Newark, DE
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