Assessment of 3M Oedema Reduction System in the Treatment of Lymphoedema Compared to Commercial Short-stretch Bandage

Inclusion Criteria (Arm):

- Mobile males or females, age 18 years or older

- Unilateral arm lymphoedema of secondary origin

- Pitting arm lymphoedema diagnosed as stage II or late stage II according to the
International Society of Lymphology staging

- Patients who require intense bandaging therapy (approx. >= 15% increase in arm volume
over the opposite healthy arm)

- Completion of all primary and adjuvant cancer treatments (surgery, chemotherapy,
radiotherapy) at least 6 months prior to randomisation

- Willing to give written informed consent and willing to comply with the study protocol

Inclusion Criteria (Leg):

- Mobile males or females, age 18 years or older

- Unilateral or bilateral leg lymphoedema of primary or secondary origin

- Pitting leg lymphoedema diagnosed as stage II or late stage II according to the
International Society of Lymphology staging

- Patients who require intense bandaging therapy

- Completion of all primary and adjuvant cancer treatments (surgery, chemotherapy,
radiotherapy) at least 6 months prior to randomisation

- Willing to give written informed consent and willing to comply with the study protocol

Exclusion Criteria (Arm):

- Known pregnancy

- Evidence of active cancer, either local or metastatic

- A period of intense daily bandaging within the last month

- Decompensated heart failure or clinically relevant kidney or liver disease

- Known relevant arterial disease of the arms

- Deep vein thrombosis or phlebitis in the last 3 months

- Paralysis of the arms

- Clinical infection of the arms (e.g. erysipelas)

- Wounds located at the study arm that require dressing change more than once a week

- History of allergic reactions to study material

- Participation in any prospective clinical study that can potentially interfere with
this study

- Participants who are, in the opinion of the clinical investigator, unsuitable for
enrolment in this study, for reasons not specified in the exclusion criteria.

Exclusion Criteria (Leg):

- Known pregnancy

- Evidence of active cancer, either local or metastatic

- A period of intense daily bandaging within the last month

- Decompensated heart failure or clinically relevant kidney or liver disease

- Deep vein thrombosis or phlebitis in the last 3 months

- Known relevant arterial disease of the legs

- Paralysis of the legs

- Clinical infection of the legs (e.g. erysipelas)

- Circumferential Lymphorrhoea

- Wounds located at the study leg that require dressing change more than once a week

- History of allergic reactions to study material

- Participation in any prospective clinical study that can potentially interfere with
this study

- Participants who are, in the opinion of the clinical investigator, unsuitable for
enrolment in this study, for reasons not specified in the exclusion criteria.