A Study of LY3209590 in Participants With Type 2 Diabetes Mellitus
| Status: | Recruiting |
|---|---|
| Conditions: | Diabetes, Diabetes |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 2/7/2019 |
| Start Date: | November 15, 2018 |
| End Date: | December 30, 2019 |
| Contact: | There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or |
| Email: | clinicaltrials.gov@lilly.com |
| Phone: | 1-317-615-4559 |
A Phase 2, Randomized, Open-Label Trial to Evaluate the Safety and Efficacy of LY3209590 in Study Participants With Type 2 Diabetes Mellitus Previously Treated With Basal Insulin
The reason for this study is to see if the study drug LY3209590 is safe and effective in
participants with type 2 diabetes that have already been treated with basal insulin.
participants with type 2 diabetes that have already been treated with basal insulin.
Inclusion Criteria:
- Type 2 diabetes mellitus according to the World Health Organization (WHO) criteria
treated with basal insulin and up to 3 of the following oral antihyperglycemic
medication (OAM):
- dipeptidyl peptidase-4 (DPP-4) inhibitors
- sodium-glucose cotransporter (SGLT-2) inhibitors
- biguanides
- alpha-glucosidase inhibitors
- sulfonlyureas
- HbA1c value of 6.5% to 10%, inclusive
- Body mass index (BMI) between 20 and 45 kilograms per meter squared (kg/m2), inclusive
Exclusion Criteria:
- Type 1 diabetes mellitus or latent autoimmune diabetes
- Any episodes of severe hypoglycemia and/or hypoglycemia unawareness within the 6
months prior to screening
- Any of the following cardiovascular (CV) conditions: acute myocardial infarction, New
York Heart Association Class III or IV heart failure, or cerebrovascular accident
(stroke)
- Acute or chronic hepatitis, or obvious clinical signs or symptoms of any other liver
disease
- Estimated glomerular filtration rate (eGFR) <30 milliliters/minute/1.73 m2
- Active or untreated malignancy
- Chronic (>14 days) systemic glucocorticoid therapy
We found this trial at
38
sites
3200 Tower Oaks Boulevard
Rockville, Maryland 20852
Rockville, Maryland 20852
Principal Investigator: Helena Rodbard
Phone: 301-770-7373
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2010 Wilshire Boulevard
Los Angeles, California 90057
Los Angeles, California 90057
213-413-2500
Principal Investigator: Juan P Frias
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7940 Floyd Curl Dr.
San Antonio, Texas 78229
San Antonio, Texas 78229
210-949-0122
Principal Investigator: Douglas S. Denham
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500 Chase Parkway
Waterbury, Connecticut 06708
Waterbury, Connecticut 06708
203-419-4420
Principal Investigator: Joseph Soufer
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2000 East Greenville Street
Anderson, South Carolina 29621
Anderson, South Carolina 29621
Principal Investigator: C. Wilson Sofley
Phone: 8645125738
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Austin, Texas 78731
Principal Investigator: Thomas C Blevins
Phone: 512-334-3505
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Billings, Montana 59101
Principal Investigator: Justen Rudolph
Phone: 406-237-8500
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Birmingham, Alabama 35205
Principal Investigator: David DeAtkine Jr.
Phone: 205-327-1077
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Blackfoot, Idaho 83221
Principal Investigator: Gary Soucie
Phone: 208-643-0006
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Charlotte, North Carolina 28204
Principal Investigator: Karlton S Pettis
Phone: 704-372-9393
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Concord, California 94520
Principal Investigator: Anna R Chang
Phone: 925-687-8860
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Cooper City, Florida 33024
Principal Investigator: Lorena Lewy-Alterbaum
Phone: 754-263-2000
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Corvallis, Oregon 97330
Principal Investigator: Michael C Chen
Phone: 541-754-1398
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Dallas, Texas 75230
Principal Investigator: Julio Rosenstock
Phone: 972-566-7799
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Escondido, California 92026
Principal Investigator: Timothy S Bailey
Phone: 760-466-1530
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Fall River, Massachusetts 02721
Principal Investigator: Tamer Yacoub
Phone: 508-672-7450
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Fresno, California 93720
Principal Investigator: Paul C Norwood
Phone: 559-261-0992
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Greenbrae, California 94904
Principal Investigator: Linda M Gaudiani
Phone: 415-461-9113
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Honolulu, Hawaii 96814
Principal Investigator: David Fitz-Patrick
Phone: 808-531-6886
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Huntington Park, California 90255
Principal Investigator: Stanley Hsia
Phone: 323-588-1968
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Idaho Falls, Idaho 83404
Principal Investigator: Carl D Vance
Phone: 208-542-6005
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Lancaster, California 93534
Principal Investigator: Kanagaratnam Sivalingam
Phone: 646-642-6189
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Las Vegas, Nevada 89102
Principal Investigator: Betsy M Palal
Phone: 702-736-5161
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Little Rock, Arkansas 72205
Principal Investigator: Kevin D Roberts
Phone: 501-907-9170
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Manassas, Virginia 20110
Principal Investigator: Nabil Andrawis
Phone: 703-330-1112
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Mauldin, South Carolina 29662
Principal Investigator: Anne Tuggle
Phone: 864-680-0762
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Monterrey, Nuevo León 64460
Principal Investigator: Jose Gerardo Gonzalez Gonzalez
Phone: 528183465540
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Nashua, New Hampshire 03063
Principal Investigator: Robert J Silver
Phone: 603-577-7574
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New Port Richey, Florida 34652
Principal Investigator: Antonio Pinero Pilona
Phone: 727-849-4131
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1010 24th Avenue Northwest
Norman, Oklahoma 73069
Norman, Oklahoma 73069
Principal Investigator: Lisa Connery
Phone: 405-701-8999
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1020 Walnut St
Philadelphia, Pennsylvania 19107
Philadelphia, Pennsylvania 19107
(215) 955-6000
Principal Investigator: Serge Jabbour
Phone: 215-955-1925
Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
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Renton, Washington 98057
Principal Investigator: Leslie Klaff
Phone: 425-251-1720
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Seattle, Washington 98101
(888) 862-2737
Principal Investigator: Grace Lee
Phone: 206-223-6600
Virginia Mason Medical Center Established in 1920, Virginia Mason began as an 80-bed hospital with...
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Topeka, Kansas 66606
Principal Investigator: Alan G Wynne
Phone: 785-368-0490
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Tustin, California 92780
Principal Investigator: Joanna T Van
Phone: 714-734-7944
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Uniontown, Pennsylvania 15401
Principal Investigator: Paul Hartley
Phone: 724-912-0033
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1031 Office Park Road
West Des Moines, Iowa 50265
West Des Moines, Iowa 50265
Principal Investigator: Anuj Bhargava
Phone: 515-329-6800
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West Palm Beach, Florida
Principal Investigator: Barry Horowitz
Phone: 561-802-3060
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