A Study of Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)
Status: | Completed |
---|---|
Conditions: | Neurology, Neurology |
Therapuetic Areas: | Neurology |
Healthy: | No |
Age Range: | 18 - 64 |
Updated: | 11/17/2018 |
Start Date: | April 2009 |
End Date: | June 2012 |
Multiple Subcutaneous Doses of LY2127399, an Anti-BAFF Human Antibody, in Subjects With Relapsing-Remitting Multiple Sclerosis
To look at the ability of LY2127399 to reduce magnetic resonance imaging (MRI) lesions at 12,
16, 20, and 24 weeks compared to placebo.
16, 20, and 24 weeks compared to placebo.
Inclusion Criteria:
- 18 through 64 years of age diagnosed with RRMS, who can walk without aid or rest for
at least 200 meters (approximately 1/10 of a mile).
- Women who can become pregnant must use birth control.
Exclusion Criteria:
- Have had a live vaccination within 12 weeks before randomization, or intend to have a
live vaccination during the course of the study.
- Have had had recent surgery or are scheduled to have surgery during the study.
- Are immunocompromised or have evidence of active infection [such as hepatitis,
tuberculosis or, human immunodeficiency virus (HIV)].
- Have been on certain drugs that are being studied for RRMS or have recently received
prescription drugs to treat RRMS.
- Have had a recent serious infection.
- Have serious or uncontrolled illnesses other than RRMS.
- Have clinically significant blood test values.
- Have multiple or severe drug allergies.
- Have contraindications for MRI "scanning" or claustrophobia (fear of an enclosed
space) that cannot be managed.
We found this trial at
28
sites
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